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Cat. No. Product Name Information
PC-35969

PF-06873600

CDK2/4/6 inhibitor

PF-06873600 (Ebvaciclib, PF06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.
PC-35809

CDK9 inhibitor HH1

CDK9 inhibitor

CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor.
PC-35808

MC180295

CDK9 inhibitor

MC180295 (MC-180295, MC 180295) is a novel potent, highly selective CDK9 inhibitor with IC50 of 5 nM, displays >22-fold selectivity over other CDKs.
PC-35787

LY3143921

Cdc7 inhibitor

LY3143921 (LY-3143921) is an orally available, potent, selective inhibitor of Cdc7 kinase inhibitor, inhibits CDC7/DBF4 I and pMCM2 (S53) with IC50 values of 3.3 nM and 290 nM, respectively..
PC-35688

JSH-150

CDK9 inhibitor

JSH-150 (JSH150) is a potent, highly selective inhibitor of CDK9 kinase with IC50 of 1 nM in the biochemical assays, displays 300-10000-fold selectivity over other CDK kinase family members (CDK7 IC50=1.72 uM).
PC-35631

iCDK9

CDK9 inhibitor

iCDK9 (i-CDK9) is a potent, highly selective CDK9 inhibitor (IC50<0.4 nM, CDK9-CycT1 kinase), exhibits >600-fold selectivity toward CDK1-CycB, CDK2-CycA, CDK4-CycD1, CDK7-CycH-MAT1 and CDK8-CycC.
PC-35630

Amt-87

Amt-87 is a HIV latency-reversal agent that reactivates latent HIV at the transcriptional level, promotes phosphorylation of CDK9 T-loop at Thr186.
PC-35532

Compound 919278

CDK12 inhibitor

Compound 919278 is a specific inhibitor of lymphotoxin β receptor (LTβR, IC50=0.169 uM), and TNF receptor superfamily member 12A (FN14)-dependent nuclear translocation of p52 (IC50=0.167 uM) via inhibiting CDK12/CCNK.
PC-35525

CDK12 inhibitor 2

CDK12 inhibitor

CDK12 inhibitor 2 is (CDK12-IN-2) is a potent, selective, non-covalent CDK12 inhibitor with IC50 of 52 nM, displays >192-fold selectivity over CDK2/7/8/9.
PC-35361

BAY-320

BUB1 inhibitor

BAY-320 (BAY320) is a potent, selective, ATP-competitive inhibitor of Bub1 kinase with IC50 of 680 nM.
PC-35250

AZD4573

CDK9 inhibitor

AZD4573 (AZD-4573) is a potent and selective inhibitor of CDK9 with IC50 of <4 nM, with fast-off binding kinetics and high selectivity versus other kinases, including other CDK family kinases.
PC-35248

Cdc7 inhibitor X

Cdc7 inhibitor

Cdc7 inhibitor X is a potent inhibitor of Cdc7 kinase with pIC50 of 10.01 against CDC7/DBF4 in TR-FRET assays.

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