| Cat. No. |
Product Name |
Information |
| PC-23908 |
PTPN22 inhibitor IC-11
PTPN22 inhibitor
|
I-C11 is a selective, reversible inhibitor of protein tyrosine phosphatase non-receptor type 22 (PTPN22, LYP) with IC50 of 4.6 uM. |
| PC-23638 |
PTPN22 inhibitor 8b
PTPN22 inhibitor
|
PTPN22 inhibitor 8b is a potent, selective inhibitor of lymphoid-specific tyrosine phosphatase (LYP, PTPN22) with Ki/IC50 of 110/260 nM, > 9-fold selectivity over a large panel of PTPs. |
| PC-23637 |
PTPN22 inhibitor 8b-19
PTPN22 inhibitor
|
PTPN22 inhibitor 8b-19 is a potent, selective inhibitor of protein tyrosine phosphatase non-receptor type 22 (PTPN22) with IC50 of 0.25 uM, 15.2-fold and 19.2-fold selectivity against SHP2 and PTP1B, respectively. |
| PC-23571 |
Ethoxysanguinarine
CIP2A inhibitor
|
Ethoxysanguinarine (ESG) is an effective small molecule inhibitor of cancerous inhibitor of protein phosphatase 2A (CIP2A), downregulates CIP2A and its downstream signaling molecules, c-Myc and pAkt, and induces protein phosphatase 2A (PP2A) activity. |
| PC-23570 |
CIP2A inhibitor TD52
CIP2A inhibitor
|
TD52 is a small molecule inhibitor of cancerous inhibitor of protein phosphatase 2A (CIP2A), downregulates CIP2A and p-Akt, reactivates protein phosphatase 2A. |
| PC-23195 |
SPI-112
SHP2 inhibitor
|
SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50 of 1 uM. |
| PC-23188 |
ENT-03
PTP1B inhibitor
|
ENT-03 is a centrally acting spermine bile acid, potently inhibits PTP1B with IC50 of 10 nM, induces weight loss in obese and lean rodents. |
| PC-22998 |
BN82002 hydrochloride
Cdc25 phosphatase inhibitor
|
BN82002 hydrochloride is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C. |
| PC-22857 |
CG-707
PTP4A3 inhibitor
|
CG-707 is a specfiic inhibitor of PTP4A3 (PRL-3, phosphatase of regenerating liver-3) with IC50 of 0.8 uM, selective over other 10 phosphatases, inhibits the migration and invasion of metastatic cancer cells. |
| PC-22856 |
Thienopyridone
PRL/PTP4A inhibitor
|
Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatases inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3), respectively. |
| PC-22839 |
Cyclosporin A
PP2B inhibitor
|
Cyclosporin A (CsA, Cyclosporine A) is a immunosuppressant agent and highly specific inhibitor of the Ca2+/calmodulin-dependent protein phosphatase PP2B with IC50 of 65 nM in rat pancreatic acinar cells. |
| PC-21910 |
G6P3510
CLas STP inhibitor
|
G6P3510 is a specific Candidatus Liberibacter spp dual-specificity phosphatase (CLas STP) with binding KD of 81.4 uM, confers plant tolerance to Candidatus Liberibacter spp. |
