| Cat. No. |
Product Name |
Information |
| PC-61276 |
II-B08
SHP2 inhibitor
|
II-B08 is a potent, selective, reversible inhibitor of PTP SHP2 with IC50 of 5.5 uM, exhibits >3-fold selectivity for SHP2 over other PTPs. |
| PC-61275 |
SHP2 inhibitor 11a-1
SHP2 inhibitor
|
SHP2 inhibitor 11a-1 is a potent, selective, cell-active SHP2 inhibitor with IC50 of 200 nM, displays >5-fold selectivity against 20 other mammalian PTPs. |
| PC-61273 |
SHP2 inhibitor 2
SHP2 inhibitor
|
SHP2 inhibitor 2 is a nove potent, selective and reversible SHP2 inhibitor with Ki of 0.51 uM. |
| PC-61272 |
GS-493
SHP2 inhibitor
|
GS-493 is a novel potent, selective SHP2 inhibitor with IC50 of 71±15 nM in enzyme assay. |
| PC-61271 |
Fumosorinone
SHP2 inhibitor
|
Fumosorinone is a novel potent, selective protein tyrosine phosphatase SHP2 inhibitor with IC50 of 6.31 uM. |
| PC-61176 |
NSC 87877
SHP1/2 inhibitor
|
NSC 87877 is potent, selective protein tyrosine phosphatase SHP1 and SHP2 with IC50 of 318 and 355 nM, respectively, also inhibits dual-specificity phosphatase 26 (DUSP26). |
| PC-61175 |
RR601
DUSP5 inhibitor
|
RR601 is a potent, selective protein tyrosine phosphatase DUSP5, PTP1B and SHP-2 inhibitor with IC50 of 36 uM, 2.1 and 1.1 uM respectively, 8-fold selectivity for PTP1B versus DUSP5. |
| PC-60897 |
ML400
LMPTP inhibitor
|
ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases. |
| PC-60896 |
LMPTP inhibitor 23
LMPTP inhibitor
|
LMPTP inhibitor 23 is a potent, selective, orally bioavailable low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 0.8 uM. |
| PC-60895 |
MLS-0322825
LMPTP inhibitor
|
MLS-0322825 is a novel potent low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 3.3 uM. |
| PC-60691 |
BCI-215
DUSP-MKP inhibitor
|
BCI-215 (BCI215) is a potent, tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. |
| PC-60664 |
NSC117079
PHLPP inhibitor
|
NSC117079 is a selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
