| Cat. No. |
Product Name |
Information |
| PC-22168 |
SCP1 inhibitor GR-28
SCP1/REST inhibitor
|
SCP1 inhibitor GR-28 is a covalent small molecule inhibitor of small C-terminal domain phosphatase 1 (SCP1) with kinact/KI 1383 min-1 M-1, causes degrades REST protein in REST-dependent glioblastoma cells. |
| PC-21980 |
SBI-0802767
LMPTP inhibitor
|
SBI-0802767 is a potent, selective low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 239 nM, remarkably selective over class I tyrosine-specific and dual-specific PTPs. |
| PC-21979 |
LMPTP inhibitor 6g
LMPTP inhibitor
|
LMPTP inhibitor 6g is a potent, selective, uncompetitive low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 83 nM, >1000-fold selective over other phosphatases. |
| PC-21978 |
LMPTP inhibitor 5d
LMPTP inhibitor
|
LMPTP inhibitor 5d is a potent, selective low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 20 nM, >1000-fold selective over other phosphatases. |
| PC-21977 |
LMPTP inhibitor 23 dihydrochloride
LMPTP inhibitor
|
LMPTP inhibitor 23 dihydrochloride is a potent, selective, orally bioavailable low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 0.8 uM. |
| PC-21976 |
Raphin1 acetate
PPP1R15B inhibitor
|
Raphin1 acetate (PPP1R15B inhibitor Raphin1) is a potent, selective, BBB-penetrant, orally bioavailable inhibitor of regulatory subunit of protein phosphatase 1, PPP1R15B, binds to the R15B-PP1c holophosphatase with Kd of 33 nM, 30-fold selective in binding R15B-PP1c over R15A-PP1c and does not bind to PP1c. |
| PC-21911 |
G6P6373
CLas STP inhibitor
|
G6P6373 is a specific Candidatus Liberibacter spp dual-specificity phosphatase (CLas STP) with binding KD of 24 uM, confers plant tolerance to Candidatus Liberibacter spp. |
| PC-21910 |
G6P3510
CLas STP inhibitor
|
G6P3510 is a specific Candidatus Liberibacter spp dual-specificity phosphatase (CLas STP) with binding KD of 81.4 uM, confers plant tolerance to Candidatus Liberibacter spp. |
| PC-21504 |
PRL inhibitor Cmpd-43
PRL inhibitor
|
PRL inhibitor Cmpd-43 is a specific small molecule inhibitor and detrimerizer of phosphatase of regenerating liver (PRL), significantly decreases PRL1 trimer formation inside the cell. |
| PC-21456 |
NGD61181
SHIP2 inhibitor
|
NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2. |
| PC-21455 |
SHIP1 inhibitor 23
SHIP1 inhibitor
|
SHIP1 inhibitor 23 is a small molecule SHIP1 inhibitor with IC50 of 6.5 uM in in the ratio pAKT/tAKT determined by Alpha SureFire assays. |
| PC-21454 |
AS1938909
SHIP2 inhibitor
|
AS1938909 is a potent, selective and competitive SHIP2 inhibitor with Ki value of 0.44 uM (human SHIP2), shows significant selectivity over other related phosphatases. |
