| Cat. No. |
Product Name |
Information |
| PC-60149 |
VU6010608
|
A potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM. |
| PC-42137 |
(S)-MCPG
|
The active isomer of (RS)-MCPG, an non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist.. |
| PC-42138 |
JNJ-16259685
|
aA highly potent, selective, non-competitive and centrally active mGluR1 antagonist with Ki of 0.34 nM. |
| PC-42124 |
FPTQ
|
A potent, specific and allosteric mGluR1 antagonist with IC50 of 6 nM and 1.4 nM for human and mouse mGluR1, respectively.. |
| PC-42205 |
VU-0364770
|
A potent, selective, systemically active positive allosteric modulator of mGlu4R with EC50 of 1.1 uM. |
| PC-42136 |
DFMTI
|
A potent, selective, brain penetrant and orally active mGluR1 antagonist with 4.3 nM and 3.6 nM for huam and rat mGluR1, respectively. |
| PC-42134 |
CFMTI
|
A potent, selective, allosteric and oral mGluR1 antaognist with IC50 of 2.6 and 2.3 nM for human and rat mGluR1, respectively. |
| PC-45423 |
JNJ-42153605
|
A potent, selective positive allosteric modulator of mGlu2 receptor with EC50 of 17 nM. |
| PC-42135 |
Ro 67-7476
|
A potent, selective positive allosteric modulator (potentiator) of rat mGlu1R with pEC50 of 6.76 for the potentiation of 3 uM glutamate-induced Ca2+ int currents. |
| PC-42140 |
PHCCC
|
A potent, selective allosteric potentiator of mGluR4 with EC50 of 4.1 uM, also is aselective antagonist of group mGlu1 receptors. |
| PC-42118 |
(RS)-MCPG
|
A non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. |
| PC-42119 |
E4CPG
|
A non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist.. |
