| Cat. No. |
Product Name |
Information |
| PC-60460 |
MK-7145
ROMK inhibitor
|
MK-7145 is a potent, selective, and oral renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 68 nM. |
| PC-60338 |
BL-1249
TREK channel inhibitor
|
BL-1249 (BL1249) is a potent K2P2.1 (TREK-1) channel activator, enhance the activity of TREK1 currents and produces relaxation of 30 mM KCl-induced contractions in rat bladder strips with EC50 of 1.12 uM. |
| PC-60337 |
ML335
TREK channel inhibitor
|
ML-335 (ML335) is a novel potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 14.3 and 5.2 uM, respectively. |
| PC-60336 |
ML402
TREK channel inhibitor
|
ML402 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 13.7 and 5.9 uM, respectively. |
| PC-60229 |
NS15370
Kv.7 activator
|
NS15370 is a highly potent positive modulator of Kv7 channels with EC50 of 100 nM (Kv7.2-Kv7.5). |
| PC-60228 |
ML-213
|
ML213 is a novel potent, selective KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) activator with EC50 of 230 and 510 nM, respectively. |
| PC-60191 |
ML67-33
K2P potassium channel activator
|
ML67-33 is a low micromolar (EC50=9.7 uM, K2P2.1), selective activator of temperature- and mechano-sensitive K2P potassium channels. |
| PC-42123 |
Nigericin sodium salt
|
An ionophore antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes. |
| PC-45091 |
NS-1643
hERG activator
|
A small molecule activator of hERG channels that enhances the magnitude of wild-type hERG current in a concentration- and voltage-dependent manner with EC50 of 10.4 uM at -10 mV. |
| PC-45127 |
Flupirtine
Kv7 activator
|
A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties. |
| PC-45126 |
Flupirtine maleate
Kv7 activator
|
Flupirtine maleate (D-9998) is a selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties. |
| PC-42069 |
PAP-1
Kv1.3 inhibitor
|
PAP-1 is a potent, selective small molecule lymphocyte K+ channel Kv1.3 blocker with EC50 of 2 nM. |
