| Cat. No. |
Product Name |
Information |
| PC-42381 |
GAL-021
BKCa inhibitor
|
GAL-021 is a respiratory stimulant that acts as a potent calcium-activated potassium (BKCa, KCa1.1) channel blocker blocker. |
| PC-46030 |
Dronedarone
Potassium channel inhibitor, USP11 inhibitor
|
Dronedarone (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats. |
| PC-45962 |
Dronedarone hydrochloride
|
Dronedarone hydrochloride (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats. |
| PC-45472 |
Azimilide dihydrochloride
hERG inhibitor
|
Azimilide dihydrochloride is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively. |
| PC-45471 |
Azimilide
hERG inhibitor
|
Azimilide (NE-10064) is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel, blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively. |
| PC-47402 |
Quinidine
|
A class I antiarrhythmic agent (Ia) that works by blocking the fast inward sodium current (INa). |
| PC-26200 |
JX3212
Kir4.1 Inhibitor
|
JX3212 is a potent, specific and brain penetrant inhibitor of inwardly rectifying potassium channel 4.1 (Kir4.1, KCNJ10) with IC50 of 0.28 uM (−120 mV) and 0.19 uM (+50 mV). |
| PC-26171 |
Apamin TFA
SK channel inhibitor
|
Apamin (Apamine) TFA is a peptide neurotoxin found in apitoxin and selective small conductance Ca(2+)-activated K(+) (SK(Ca)) channel blocker, exhibits anti-inflammatory and anti-fibrotic activity. |
| PC-26170 |
Apamin
SK channel inhibitor
|
Apamin (Apamine) is a peptide neurotoxin found in apitoxin and selective small conductance Ca(2+)-activated K(+) (SK(Ca)) channel blocker, exhibits anti-inflammatory and anti-fibrotic activity. |
| PC-26105 |
ICA73
KCNQ2 activator
|
ICA‐069673 (ICA73) is a selective activator of KCNQ2 potassium channel (Kv7.2), acts within the voltage-sensor domain (VSD), shows selective effects on KCNQ2 over KCNQ3. |
| PC-26104 |
ztz240
KCNQ2 activator
|
ztz240 is a potent, selective activator of KCNQ2 potassium channel (Kv7.2) with EC50 of 5.8 uM on outward current of KCNQ2 channels. |
| PC-26103 |
E0714
Kv7.2 agonist
|
E0714 (E-0714) is a potent, specific agonist of Kv7.2 potassium channel (KCNQ2) with EC50 of 1.9 uM and 0.021 uM for Kv7.2 and Kv7.2/7.3 currents, with no significant activation of Kv7.1/7.3/7.4/7.5. |
