| Cat. No. |
Product Name |
Information |
| PC-49839 |
Retigabine
Kv7 opener
|
Retigabine (D-23129, XEN496) is an anticonvulsant compound and KV7 channel agonist (opener), enhances activation of KCNQ2/Q3 potassium channels. |
| PC-49797 |
ACOU001
KV7.4 activator
|
ACOU001 (ACOU 001) is a potent small-molecule agonist of Kv7.4 (KCNQ4) channel with potential effect against ge-related hearing loss (ARHL) and other hearing impairments related to compromised KV7.4 function. |
| PC-49796 |
ACOU085
KV7.4 activator
|
ACOU085 (ACOU 085) is a potent small-molecule agonist of Kv7.4 (KCNQ4) channel with higher potency than ML-213 in the nanomolar range. |
| PC-49468 |
TASK inhibitor F3
TASK Channel inhibitor
|
TASK inhibitor F3 is a potent, selective blocker of TWIK-related acid-sensitive K+ (TASK) channels with IC50 of 148 nM (TASK-1). |
| PC-38848 |
KV10.1 inhibitor compound 1
Kv10.1 inhibitor
|
KV10.1 inhibitor compound 1 is a selective inhibitor of the voltage-gated potassium channel KV10.1 with IC50 of 740 nM. |
| PC-38639 |
3hi2one-G4
GIRK4 activator
|
3hi2one-G4 is a highly selective small molecule activator targeting GIRK4 homomeric channels, does not activate GIRK2, GIRK1/2 or GIRK1/4 channels. |
| PC-38493 |
RY785
Kv2 channel inhibitor
|
RY785 (RY-785) is a potent, selective voltage-gated potassium (Kv2) channels inhibitor with IC50 of 50 nM for Kv2.1 channel, possesses good selectivity over Kv1.2 (IC50>10 uM). |
| PC-38451 |
BMS-191011
KCa1.1/BK opener
|
BMS-191011 (BMS-A) is a small molecule activator of large-conductance calcium-activated potassium (KCa1.1/BK) channels, increases current to 126% over control at 1 uM. |
| PC-73403 |
Bafrekalant
Potassium channel blocker
|
Bafrekalant is a small molecule potassium channel blocker with the potential for the research of breathing disorders. |
| PC-73253 |
Lu AA41178
Kv7 channels opener
|
Lu AA41178 is a potent, pan-selective Kv7.2-7.5 opener with EC50 of 1.5, 0.6 20.5, and 37.0 uM for Kv7.2, Kv7.2/7.3, Kv7.4 and Kv7.5, respectively. |
| PC-73241 |
KNa1.1 inhibitor 31
KNa1.1 (Slack) inhibitor
|
KNa1.1 inhibitor 31 is a potent, selective, orally available inhibitor of sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) with IC50 of 40 nM (hKNa1.1 WT). |
| PC-73222 |
NS8593 hydrochloride
SK channel inhibitor
|
NS8593 is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor, reversibly inhibits recombinant SK3-mediated currents with potencies around 100 nM. |
