| Cat. No. |
Product Name |
Information |
| PC-28584 |
S-thanatin
Antimicrobial peptide
|
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity, inhibits the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, binds negatively charged LPS and anionic lipid, ihhibits membrane respiration, exhaustes the intracellular potential, and releases periplasmic material, leding to cell death. |
| PC-28583 |
Thanatin TFA
Antimicrobial, LPS transport inhibitor
|
Thanatin TFA is a 21-residue inducible insect defense peptide within antimicrobial activity against fungi and some Gram-positive bacteria with MIC of 0.6-20 uM, disrupts bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase, inhibits LPS transport (Lpt) LptC-LptA interaction, disrupting the assembly of the Lpt protein machinery. |
| PC-28582 |
Thanatin
Antimicrobial, LPS transport inhibitor
|
Thanatin is a 21-residue inducible insect defense peptide within antimicrobial activity against fungi and some Gram-positive bacteria with MIC of 0.6-20 uM, disrupts bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase, inhibits LPS transport (Lpt) LptC-LptA interaction, disrupting the assembly of the Lpt protein machinery. |
| PC-28531 |
S. aureus ClpC activator Cpd-8
S. aureus ClpC activator
|
S. aureus ClpC activator Cpd-8 is a small-molecule activator of the Staphylococcus aureus ClpC/ClpP AAA+ protease with EC50 of 12 uM, binds to ClpC N-terminal domain (NTD), induces ClpC/ClpP-independent toxicity in Staphylococcus aureus. |
| PC-28530 |
S. aureus ClpC activator Cpd-10
S. aureus ClpC activator
|
S. aureus ClpC activator Cpd-10 is a small-molecule activator of the Staphylococcus aureus ClpC/ClpP AAA+ protease with EC50 of 4.4 uM, induces ClpC/ClpP-independent toxicity in Staphylococcus aureus |
| PC-28495 |
Kasugamycin hydrochloride
Antibiotic
|
Kasugamycin hydrochloride (Ksg) is a small ribosomal subunit-targeting antibiotic, binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation, possesses anti-infective activity. |
| PC-28494 |
Kasugamycin
Antibiotic
|
Kasugamycin (Ksg) is a small ribosomal subunit-targeting antibiotic, binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation, possesses anti-infective activity. |
| PC-28393 |
NDM-552
PBP2 inhibitor
|
NDM-552 is a Gram-positive selective antibacterial agent that potentially targets penicillin-binding protein 2 (PBP2)-associated cell wall biosynthesis, exhibits activity against Gram-positive pathogens including S. aureus, Enterococcus faecium, and Staphylococcus epidermidis with MIC of 1-2 ug/mL. |
| PC-28263 |
Murepavadin TFA
Antibiotic, MRGPRX2 agonist
|
Murepavadin TFA (POL7080) is a highly potent, specific, macrocycle Pseudomonas antibiotic, activates mast cells via MRGPRX2 and MrgprB2. |
| PC-28185 |
MtbIMPDH inhibitor 31
Mtb GuaB inhibitor
|
MtbIMPDH inhibitor 31 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, MtbIMPDH) with IC50 of 0.52 uM. |
| PC-28184 |
MtbIMPDH2 inhibitor P41
GuaB2 inhibitor
|
MtbIMPDH2 inhibitor P41 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, MtbIMPDH) with Ki app of 17 nM for MtbIMPDH2ΔCBS, displays significant activity against Mtb strain H37Rv in minimal BSA-free medium with MIC of 5 uM. |
| PC-28181 |
Mtb GuaB-IN-2
Mtb GuaB inhibitor
|
Mtb GuaB-IN-2 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, IMPDH) with IC50 of 0.2 nM. |
