| Cat. No. |
Product Name |
Information |
| PC-24353 |
H052
S. aureus α-hemolysin inhibitor
|
H052 is a highly potent S. aureus α-hemolysin (Hla) inhibitor, protect U937 cells from Hla-induced Ca2+ influx with EC50 of 0.01 uM, restores Hla-induced damage of host cell integrity. |
| PC-24346 |
NCBP1
Antibacterial
|
NCBP1 is a plant-derived, 11 amino acid, noncanonical antibacterial peptide with dual activity against multidrug-resistant bacterial and fungal pathogens, by targeting phosphatidylglycerol and cardiolipin in bacterial membrane, resulting in membrane damage and dysfunction. |
| PC-24340 |
DNA gyrase inhibitor 35
2088347-91-3
|
DNA gyrase inhibitor 35 is potent small molecule DNA gyrase inhibitor with IC50 of 1.2 μM of E.coli DNA gyrase, also shows low micromolar inhibition of E. coli topoisomerase IV and of the respective Staphylococcus aureus homologues. |
| PC-24339 |
Astrazeneca Arylaminotriazine
DNA gyrase inhibitor
|
Astrazeneca Arylaminotriazine is a promising DNA gyrase inhibitor with profound antibacterial activity. |
| PC-24338 |
10-F05
FabH/MiaA inhibitor
|
10-F05 is a covalent small molecule inhibitor of bacterial β-ketoacyl-acyl carrier protein synthase III (FabH) and MiaA tRNA prenyltransferase, demonstrates broad-spectrum antibacterial effectiveness (MIC=2.5 uM, S. flexneri). |
| PC-24315 |
Lariocidin
Antibiotic
|
Lariocidin (LAR) is a novel ribosome-targeting lasso peptide antibiotic inhibit bacterial growth by binding to the ribosome and interfering with protein synthesis. |
| PC-24305 |
P2-56-3
Rifampin potentiator
|
P2-56-3 is small-molecule sensitizer of antibiotic-resistant gram-negative ESKAPE pathogens, potentiates rifampin against antibiotic-resistant strains of Acinetobacter baumannii and Klebsiella pneumoniae, disrupts the outer membrane of A. baumannii. |
| PC-24304 |
Rifampin
Antibiotic
|
Rifampin (Rifampicin) is a potent and broad spectrum antibiotic against bacterial pathogens, also has anti-influenza virus and anti-orthopoxvirus activities. |
| PC-24301 |
Fosfomycin sodium
Antibiotic
|
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis, shows a wide range antibacterial activity, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. |
| PC-24300 |
Fosfomycin calcium
Antibiotic
|
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis, shows a wide range antibacterial activity, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. |
| PC-24236 |
FBX-1991
H. pylori FabX inhibitor
|
FBX-1991 is a potent, specific small molecule inhibitor of Helicobacter pylori (H. pylori) dehydrogenase/isomerase FabX with IC50 of 0.158 uM, shows potent antibacterial activity against strain BHKS211 with MIC of 16 ug/mL. |
| PC-24201 |
ChlaDUB1 inhibitor 27a
ChlaDUB1 inhibitor
|
ChlaDUB1 inhibitor 27a is a specific covalent inhibitor of bacterial chlamydial deubiquitinase 1 (ChlaDUB1) with IC50 of 0.97 uM, inhibits chlamydial growth with IC50 of 25.6 ug/mL. |
