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Request The Product List ofBacterial Bacterial

Bacteria constitute a large domain of prokaryoticmicroorganisms. Antibiotics (also called antibacterials) are a type of antimicrobial drug used in the treatment and prevention of bacterial infections, a limited number of antibiotics also possess antiprotozoal activity. Together with vaccination, antibiotics have led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access have also led to their overuse, prompting bacteria to develop resistance.

A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. In vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.

 
 

Cat. No. Product Name Information
PC-45351

Demeclocycline hydrochloride

A tetracycline antibiotic that acts by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA which impairs protein synthesis by bacteria.
PC-42273

Antibiotic-5d

A synthetic antimicrobial compound that antibacterial activity in vitro against various Gram-positive and Gram-negative bacteria, fungi and yeast..
PC-45284

Sancycline

A semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin..
PC-45148

Rifabutin

A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. .
PC-45277

Garenoxacin mesylate hydrate

A quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections..
PC-45276

Garenoxacin

A quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections..
PC-42192

DprE1-IN-25

A potent, noncovalent DprE1 inhibitor with IC50 of 43 nM, shows activity against Mycobacterium tuberculosis (Mtb) in vitro with MIC of 0.39 uM..
PC-45087

AFN-1252

A potent inhibitor of bacterial enoyl-ACP reductase FabI.
PC-42189

Nanchangmycin

A polyether ionophore antibiotic isolated from Streptomyces nanchangensis NS3226 that shows antibacterial and antiviral properties.
PC-45261

Salinomycin sodium

A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration.
PC-45354

Capreomycin sulfate

A peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. .
PC-45426

MUT-056399

A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli.

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