Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-Bacterial

Request The Product List ofBacterial Bacterial

Bacteria constitute a large domain of prokaryoticmicroorganisms. Antibiotics (also called antibacterials) are a type of antimicrobial drug used in the treatment and prevention of bacterial infections, a limited number of antibiotics also possess antiprotozoal activity. Together with vaccination, antibiotics have led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access have also led to their overuse, prompting bacteria to develop resistance.

A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. In vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.

 
 

Cat. No. Product Name Information
PC-45926

Moxifloxacin

Antibiotic

Moxifloxacin is a fourth-generation synthetic fluoroquinolone, broad-spectrum antibacterial agent that is active against both Gram-positive and Gram-negative bacteria; inhibits DNA gyrase and topoisomerase IV.
PC-42665

Gatifloxacin

Bacterial DNA gyrase inhibitor

Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
PC-42048

Faropenem daloxate

Beta-lactam antibiotic

Faropenem daloxate (Faropenem medoxil) is a daloxate ester prodrug of Faropenem with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes, a beta-lactam antibiotic.
PC-42714

Pretomanid

Mtb inhibitor

Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid.
PC-27472

Luxafimloc

FimH inhibitor

Luxafimloc is a small molecule Escherichia coli fimbrial (FimH) adhesin inhibitor.
PC-27434

Saeamid-1

MRSA SaeS inhibitor

Saeamid-1 is a potential antivirulence compound and SaeS-targeting antagonist against methicillin-resistant Staphylococcus aureus (MRSA), reduces hemolytic activity and biofilm biomass while having only limited effects on MRSA growth.
PC-27401

Geneticin

Antibiotic

Geneticin (G418, Antibiotic G-418) is an aminoglycoside antibiotic with a structure similar to gentamicin, is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis.
PC-27400

Pefloxacin

Antibiotic

Pefloxacin is a fluoroquinolone antibiotic used for various bacterial infections, inhibits Plasmodium falciparum in vitro, inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase.
PC-27399

Amifloxacin

Antibiotic

Amifloxacin (WIN 49375) is an quinolone carboxylic acid antibacterial agent with MIC of 4 ug/mL against aminoglycoside-resistant Pseudomonas aeruginosa, shows broad activity for gentamicin-resistant gram-negative bacilli.
PC-27374

OSSL-632214

Mtb TrxB2 inhibitor

OSSL-632214 (OSSL_632214) is a potent anti-Mtb compound with MIC of 3.13-6.25 μg/mL in vitro, possibly acts by targeting Thioredoxin reductase (TrxB2, Rv3913) and inducing lipid peroxidation in Mtb.
PC-27279

Mtb IMPDH2-IN-2

Mtb IMPDH2 inhibitor

MtbIMPDH2-IN-2 is a potent, selective Mycobacterium tuberculosis (Mtb) inosine 5'-monophosphate dehydrogenase 2 (MtbIMPDH2) inhibitor with IC50 of 12 nM, and MIC of 12 uM for Mtb, blocks the biosynthesis of guanine nucleotides.
PC-27208

Kalamycin

METTL1 inhibitor, Antibiotic

Kalamycin (Kalafungin, U-19718, NSC137443) is an antibiotic, antimicrobial agent and β-lactamase inhibitor from marine Streptomyces, also is a potent inhibitor of METTL1 methyltransferase activity with IC50 of 8.9 uM, demonstrates potent antileukemia efficacy, also shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com