| Cat. No. |
Product Name |
Information |
| PC-38471 |
GW779439X
PASTA kinase Stk1 inhibitor
|
GW779439X is a small-molecule kinase inhibitor that sensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics via inhibition of the PASTA kinase Stk1. |
| PC-38420 |
LpxC-IN-5
LpxC inhibitor
|
LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with IC50 of 20 nM, shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 ug/mL, respectively. |
| PC-38406 |
QZN 34
PqsR inhibitor
|
QZN 34 is a small molecule pseudomonas aeruginosa PQS quorum-sensing system (PqsR) inhibitor with IC50 of 15 uM, kills planktonic Gram-positives (S. aureus, MIC 6.25 uM) but not Gram-negatives. |
| PC-38403 |
Morponidazole
Antibiotic
|
Morponidazole is a nitroimidazoles antibiotic for bacterial infections. |
| PC-38364 |
MCB3681
C. difficile inhibitor
|
MCB3681 (Oxaquin, MCB 3681) is a quinolonyl-oxazolidinone bactericidal antibiotic, has activity in vitro against Gram-positive bacteria. |
| PC-38363 |
LFF-571
Bactericidal antibiotic
|
LFF571 is a semisynthetic thiopeptide and bactericidal antibiotic that interferes with bacterial protein synthesis by inhibition of elongation factor EF-Tu, LFF571 is potent in vitro activity against C.difficile strains with MIC90 of 0.25 ug/mL. |
| PC-38362 |
MGB-BP-3
C. difficile inhibitor
|
MGB-BP-3 is a potent bactericidal antibiotic with a completely novel mode of action, selectively binds to the minor grove of microbial DNA, has the potential for Clostridioides difficile infection (CDI). |
| PC-38361 |
Ibezapolstat
DNA pol IIIC inhibitor
|
Ibezapolstat (ACX-362E) is a potent, selective, first-in-class DNA polymerase IIIC (DNA pol IIIC) inhibitor with IC50 of 51 nM (B. Subtilis pol IIIC), inhibits C. difficile efficiently (MIC50, 2 ug/mL). |
| PC-73439 |
Quabodepistat
DprE1 inhibitor
|
Quabodepistat (OPC-167832) is a highly potent antituberculosis agent with MIC of 0.00024 to 0.002 ug/mL against Mycobacterium tuberculosis, targets DprE1 (IC50=258 nM, recombinant DprE1), an essential enzyme for cell wall biosynthesis. |
| PC-73350 |
PTC-847
Ng RNR inhibitor
|
PTC-847 (PTC847) is a novel orally active inhibitor that exhibits a narrow spectrum of activity against Neisseria gonorrhoeae (N. gonorrhoeae, Ng) including MDR isolates (MIC, 0.05 to 0.1 ug/mL), directly inhibits class Ia ribonucleotide reductase (RNR). |
| PC-73349 |
PTC-672
Ng RNR inhibitor
|
PTC-672 (PTC672) is a novel orally active inhibitor that exhibits a narrow spectrum of activity against Neisseria gonorrhoeae (N. gonorrhoeae, Ng) including MDR isolates (MIC, 0.05 to 0.4 ug/mL), directly inhibits class Ia ribonucleotide reductase (RNR). |
| PC-73346 |
Xeruborbactam
β-lactamase inhibitor
|
Xeruborbactam (QPX7728) is an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM). |
