Cat. No. |
Product Name |
Information |
PC-38175 |
TP0586532
LpxC inhibitor
|
TP0586532 (TP 0586532) is a novel non-hydroxamate inhibitor of UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with IC50 of 0.101 uM, shows MIC values 2 mg/mL and 4 mg/mL for E. coli ATCC 25922 and K. pneumoniae ATCC 13883. |
PC-38041 |
ML267
Sfp-PPTase inhibitor
|
ML267 (ML 267) is a potent, small-molecule inhibitor of bacterial phosphopantetheinyl transferase Sfp-PPTase with IC50 of 0.29 uM. |
PC-38036 |
A40926
Antibiotic
|
A40926 is a glycopeptide antibiotic against gram-positive bacteria, the precursor of Dalbavancin and is very active against Neisseria gonorrhoeae.. |
PC-36006 |
ANY1
FosA inhibitor
|
ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA). |
PC-35948 |
GSK3011724A
KasA inhibitor
|
GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM), shows anti-tubercular activity (MIC H37Rv=0.8 uM). |
PC-35875 |
QcrB inhibitor TB47
QcrB inhibitor
|
QcrB inhibitor TB47 (TB47) is a novel antimycobacterial agent that fuctions as a putative respiratory complex III (QcrB) inhibitor with MIC of 0.016-0.5 ug/mL against a panel of 56 M. tuberculosis clinical isolates. |
PC-35825 |
Lethal toxin inhibitor DN1
|
Lethal toxin inhibitor DN1 is a small molecule that reduces the cytotoxicity of anthrax lethal toxin (LT) an inhibitor of LT-induced pyroptosis, acts as an antagonist of GPCR receptors type-1 angiotensin II receptor (AGTR1) and apelin receptor (APLNR) with IC50 of 1.958 and 2.280 uM, respectively. |
PC-35816 |
AgrA inhibitor F19
AgrA inhibitor
|
AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription. |
PC-35447 |
Durlobactam
β-lactamase inhibitor
|
Durlobactam (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50 of 4, 14 and 190 nM for class A β-lactamase KPC-2, class AmpC and class D OXA-24, respectively. |
PC-35421 |
ClpP inhibitor M21
ClpP inhibitor
|
ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay. |
PC-35372 |
NOSO-502
|
NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation, has MIC values of 0.5-4 ug/ml against standard Enterobacteriaceae strains and carbapenem-resistant Enterobacteriaceae (CRE) isolates that produce KPC, AmpC, or OXA enzymes and metallo-β-lactamases. |
PC-35157 |
Q151
|
Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (MtbIMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity. |