| Cat. No. |
Product Name |
Information |
| PC-20094 |
GSK692
Antimalarial
|
GSK692 (GSK-692) is an antimalarial compound that targets blood-stage activity of the Plasmodium falciparum and Plasmodium vivax parasites (Pf IC50=10 nM). |
| PC-20081 |
OTB-658
Antibiotic
|
OTB-658 (OTB658) is a novel oxazolidinone anti-tuberculosis agent, shows potent antibacterial activity against Mycobacterium tuberculosis, especially multi-drug resistant tuberculosis (MDR-TB) in vitro and in vivo. |
| PC-20080 |
NTB-3119
Antibiotic
|
NTB-3119 (NTB3119) is a novel benzothiopyranone derivative and anti-tuberculosis agent with potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains. |
| PC-20079 |
JSF-3285
KasA inhibitor
|
JSF-3285 (JSF3285) is a potent small molecule inhibitor of the M. tuberculosis β-ketoacyl synthase KasA with Kd of 70.7 nM in MST assays, shows activity against H37Rv strain with MIC 0.2 uM. |
| PC-20076 |
Torezolid phosphate
Antibiotic
|
Torezolid phosphate (DR-701, DA-7218) is the pro-drug of Tedizolid (TR-700, DA-7157), could be hydrolysed via phosphatase to form its active metabolite Tedizolid, shows good activity against several Gram positive bacteria, including Nocardia and Mycobacterium. |
| PC-20075 |
Tedizolid
Antibiotic
|
Tedizolid (TR-700, DA-7157) is an oxazolidinone antibiotic with activity against mycobacterium tuberculosis and nocardia brasiliensis with MIC50 of 0.25 ug/mL. |
| PC-20074 |
Radezolid
Antibiotic
|
Radezolid (RX-1741) is a biaryloxazolidinone antibiotic with improved activity, including against linezolid-resistant strains, demonstrates potency against Gram-positive bacteria including methicillin-resistant Staph. aureus and vancomycin-resistant enterococci. |
| PC-20073 |
TBI-223
Antibiotic
|
TBI-223 is an oxazolidinone with excellent oral bioavailability and activity against Gram-positive bacteria, works as protein synthesis inhibitor, targets an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. |
| PC-20072 |
TBI-166
Antibiotic
|
TBI-166 is a potential next-generation antituberculosis riminophenazine with activity against Mycobacterium tuberculosis (0.063 μg/ml). |
| PC-20071 |
Posizolid
Antibiotic
|
Posizolid (AZD2563) is an oxazolidinone antibiotic with activity against staphylococci, pneumococci and enterococci (MIC, 0.25-2 ug/mL), AZD2563 is equally active against the surveillance isolates. |
| PC-49758 |
COE2-2hexyl
S. aureus inhibitor
|
COE2-2hexyl is a broad-spectrum antibacterial conjugated oligoelectrolyte (COE), does not evoke bacterial resistance, inhibits methicillin-resistant S. aureus (MRSA, MT3302) with MIC of 1 ug/mL. |
| PC-49691 |
Nifuroxazide
STAT3 inhibitor
|
Nifuroxazide (NFX) is a broad-spectrum antibacterial agent, also exhibits potent inhibition of the transcription factor STAT3, also inhibits ERG-mediated transcription, is selectively bio-activated by ALDH1 enzymes over ALDH2 enzymes. |
