| Cat. No. |
Product Name |
Information |
| PC-60540 |
FD-5180
|
A novel protein kinase affinity probe.. |
| PC-60378 |
SU-5214
|
A tyrosine kinase signal transduction modulator.. |
| PC-45722 |
Naquotinib mesylate
|
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
| PC-42641 |
ARRY-380 analog
|
An analog of ARRY-380, a potent and selective HER2 inhibitor with IC50 of 8 nM. |
| PC-42524 |
CL-387785
|
A specific, irreversible, covalent EGFR inhibitor with IC50 of 0.37 nM. |
| PC-42522 |
BIBX 1382
|
A selective EGFR inhibitor with IC50 of 3 nM. |
| PC-45895 |
Lapatinib ditosylate
|
A reversible, selective dual tyrosine kinase inhibitor of both EGFR and ErbB2 with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. |
| PC-45894 |
Lapatinib
|
A reversible, selective dual tyrosine kinase inhibitor of both EGFR and ErbB2 with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. |
| PC-45997 |
AZD-9291 dimesylate
|
A potent, selective, third-generation irreversible inhibitor of mutant EGFR with IC50s of 1/12/5 nM for L858R-T790M/L858R/L861Q respectively. |
| PC-44707 |
AZD-9291 mesylate
|
A potent, selective, third-generation irreversible inhibitor of mutant EGFR with IC50s of 1/12/5 nM for L858R-T790M/L858R/L861Q respectively. |
| PC-45892 |
Gefitinib hydrochloride
|
A potent, selective, orally active EGFR inhibitor with IC50 of 23 nM. |
| PC-45893 |
Erlotinib
|
A potent, selective inhibitor of EGFR with IC50 of 2 nM. |
