| Cat. No. |
Product Name |
Information |
| PC-44667 |
CO-1686 hydrobromide
|
A potent, highly selective, irreversible inhibitor of mutant EGFR with Ki of 21.5 nM for EGFR L858R/T790M. |
| PC-44666 |
CO-1686
|
A potent, highly selective, irreversible inhibitor of mutant EGFR with Ki of 21.5 nM for EGFR L858R/T790M. |
| PC-42532 |
BMS-690514
|
A potent pan HER/VEGFR inhibitor with IC50 of 5/20/60/50 nM for EGFR/HER2/ERBB4/VEGFR2 respectively. |
| PC-45785 |
Tyrphostin AG 879
|
A potent HER2/ErbB2 inhibitor with IC50 of 1 uM. |
| PC-42386 |
RG13022
|
A potent EGFR inhibitor that inhibits EGFR autophosphorylation with IC50 of 5 uM in cell-free assays. |
| PC-42383 |
RG14620
|
A potent EGFR inhibitor that inhibits EGFR autophosphorylation with IC50 of 4 uM in cell-free assays. |
| PC-42546 |
AV-412 free base
|
A potent dual inhibitor of EGFR and ErbB2. |
| PC-42545 |
AV-412
|
A potent dual inhibitor of EGFR and ErbB2. |
| PC-46002 |
O-Desmorpholinopropyl Gefitinib
|
A metabolite of Gefitinib, which is a potent inhibitor of tyrosine phosporylation in EGFR.. |
| PC-45479 |
PD-158780
|
A highly potent, selective, ATP binding site inhibitor of EGFR with IC50 of 0.008 nM. |
| PC-45995 |
Mutated EGFR-IN-1
|
A des acryl analogue of AZD9291 that is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.. |
