| Cat. No. |
Product Name |
Information |
| PC-43202 |
Asivatrep
TRPV1 inhibitor
|
Asivatrep (PAC-14028) is a potent, selective TRPV1 antagonist with IC50 of 55 nM against capsaicin-induced Ca2+ influx in rat DRG neurons, does not inhibit or activate other TRP channels such as hTRPV2, hTRPV3, hTRPM8 and hTRPA1. |
| PC-62504 |
HC-070
TRPC4/TRPC5 inhibitor
|
HC-070 is a potent, selective, orally active inhibitor of TRPC4 and TRPC5 channel with IC50 of 9.3 and 46 nM (calcium influx inhibition), respectively. |
| PC-70337 |
GSK 2833503A
TRPC3/6 inhibitor
|
GSK 2833503A (GSK2833503A, GSK503A) is a potent, and selective inhibitor of TRPC3/6 channels with IC50 of 4 nM/5 nM, respectively. |
| PC-70336 |
GSK 2332255B
TRPC3/6 inhibitor
|
GSK 2332255B (GSK2332255B, GSK255B) is a potent, and selective inhibitor of TRPC3/6 channels with IC50 of 3 nM/21 nM, respectively. |
| PC-61124 |
AM-0902
|
AM-0902 (AMG0902) is a potent, selective, orally active TRPA1 channel antagonist with IC50 of 71 and 131 nM for rTRPA1 and hTRPA1 in Ca2+ flux assays respectively, without agonist activity (EC50>40 uM). |
| PC-60846 |
Pico145
TRPC1/4/5 inhibitor
|
Pico145 is a highly potent, subtype-selective TRPC1/4/5 channels inhibitor with potency ranged from 9 to 1300 pM, depending on the TRPC1/4/5 subtype and activation mechanism. |
| PC-60787 |
RQ-00203078
|
A potent, selective and orally available TRPM8 channel inhibitor with IC50 of 8.3 nM (hTRPM8). |
| PC-60785 |
PF-05105679
|
PF-05105679 is a potent, selective TRPM8 channel inhibitor with IC50 of 103 nM (human TRPM8 currents inhibition). |
| PC-60610 |
Larixyl acetate
TRPC6 blocker
|
Larixyl acetate is a potent, selective TRPC6 channel inhibitor with IC50 of 0.1-0.6 uM, 12- and 5-fold selectivity over related TRPC3 and TRPC7. |
| PC-70135 |
Tranilast
TRPV2 inhibitor
|
Tranilast (MK-341) is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. |
| PC-60294 |
GSK-2193874
|
GSK-2193874 (GSK2193874) is an orally active, potent, and selective blocker of TRPV4 channel with IC50 of 40 nM and 2 nM for hTRPV4 and rTRPV4, respectively. |
| PC-70051 |
A-967079
|
A-967079 (A 967079) is a potent, selective TRPA1 channel blocker with IC50 of 51 nM and 101 nM for hTRPA1 and rTRPA1, respectively. |
