| Cat. No. |
Product Name |
Information |
| PC-61374 |
Elismetrep
|
A novel specific TRPM8 channel antagonist for treatment or prevention vasomotor symptoms.. |
| PC-61156 |
ASP 7663
|
A novel potent, selective, orally active TRPA1 receptor agonist with EC50 of 0.51, 0.54 and 0.50 uM for human, rat and mouse TRPA1, respectively. |
| PC-60788 |
(S)-PBMC
|
A novel potent, selective TRPM8 antagonist with IC50 of 15.6 nM (hTRPM8). |
| PC-60786 |
WS-12
|
A potent, selective TRPM8 agonist with EC50 of 12 uM, a cooling agent. |
| PC-60742 |
DFL 23448
|
A novel potent, selective TRPM8 channel antagonist with IC50 of 10 and 21 nM in hTRPM8 HEK293 cells activated by Cooling Agent 10 or cold. |
| PC-60720 |
DD-01050
|
A potent, noncompetitive TRPV1 antagonist that abrogates capsaicin and pH-evoked TRPV1 channel activity with submicromolar activity. |
| PC-60719 |
JNJ 41876666
|
A potent, selective, orally active TRPM8 channel antaognist with IC50 of 0.8 nM, . |
| PC-60718 |
AMTB hydrochloride
|
A selective TRPM8 channel blocker with pEC50 of 6.91 in Ca(2+) influx assay, with no activity for TRPV4 (pEC50<4.6). |
| PC-60668 |
MRS 1477
|
A small molecule positive allosteric modulator of both proton and vanilloid activation of TRPV1 (EC50=21.3 uM). |
| PC-70040 |
RN-9893 hydrochloride
|
A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively. |
| PC-70039 |
RN-9893
|
A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively. |
| PC-45790 |
Clemizole hydrochloride
|
An H1 histamine receptor antagonist that substantially inhibits HCV replication by suppression of NS4B's RNA binding (IC50=24 nM) with little toxicity for the host cells. |
