| Cat. No. |
Product Name |
Information |
| PC-60025 |
AC1903
|
AC1903 is a potent, specific TRPC5 channel inhibitor with IC50 of 14.7 uM. |
| PC-60019 |
2-APB
|
2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker. |
| PC-45654 |
GSK-1016790A
TRPV4 agonist
|
GSK-1016790A is a potent TRPV4 channel agonist, induces Ca2+ influx in HEK cells expressing human TRPV4 with EC50 of 2.1 nM. |
| PC-42799 |
Icilin
TRPM8 agonist
|
Icilin (AG-3-5) is asuper-cooling agent that fuctions as a potent TRPM8 agonist with EC50 of 0.2 uM. |
| PC-45093 |
Mavatrep
TRPV1 inhibitor
|
Mavatrep (JNJ-39439335) is a selective, high-affinity TRPV1 antagonist with IC50 of 4.6 nM (inhibition of capsaicin-induced Ca(2+) influx). |
| PC-45772 |
RN-1734
TRPV4 inhibitor
|
RN-1734 (RN1734) is a potent, selective TRPV4 antagonist with IC50 of 2.3, 3.2 and 5.9 uM for hTRPV4, rTRPV4 and mTRPV4 channels, respectively. |
| PC-42419 |
AMG-9810
TRPV1 inhibitor
|
AMG-9810 is a potent, selective and competitive TRPV1 antagonist with IC50 of 24.5 and 85.6 nM for human and rat TRPV1, respectively. |
| PC-42017 |
SKF-96365 hydrochloride
|
SKF-96365 hydrochloride (SKF96365) is potent inhibitor of receptor-mediated calcium entry (RMCE) with IC50 of 8.5 and 11.7 uM for inhibition in platelets stimulated with ADP and thrombin, respectively. |
| PC-42084 |
HC-067047
TRPV4 inhibitor
|
HC-067047 (HC067047) is a potent and selective TRPV4 antagonist with IC50 of 48 nM, 133 nM, and 17 nM for human, rat, and mouse TRPV4 in cell assays, respectively. |
| PC-45632 |
Pyr10
TRPC3 inhibitor
|
Pyr10 is a novel TRPC3-selective inhibitor, inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with IC50 of 0.72 uM. |
| PC-22170 |
TRPV2 antagonist SET2
TRPV2 antagonist
|
SET2 is a potent, subtype-selective inhibitor of transient receptor potential vanilloid type 2 (TRPV2) with IC50 of 0.46 uM. |
| PC-22128 |
TH-1177
TRPV6 inhibitor
|
TH-1177 is a small molecule TRPV6 calcium channel inhibitor, effectively blocks calcium entry in LNCaP prostate cancer cells and demonstrates inhibitory effects on prostate cancer proliferation. |
