| Cat. No. |
Product Name |
Information |
| PC-73351 |
ZINC17988990
TRPV5 inhibitor
|
ZINC 17988990 is a potent, selective inhibitor of TRPV5 mediated currents, inhibits rbTRPV5/hTRPV5 with IC50 of 106/177 nM, showing marked selectivity for TRPV5 over TRPV6. |
| PC-73173 |
ML-SI3
TRPML inhibitor
|
ML-SI3 is a synthetic inhibitor of TRPML calcium channel blocker. |
| PC-73096 |
GSK3527497
TRPV4 inhibitor
|
GSK3527497 (GSK-3527497) is a potent, selective TRPV4 inhibitor with IC50 of 12 nM (hTRPV4). |
| PC-72671 |
ML2-SA1
TRPML2 agonist
|
ML2-SA1 is a potent, selective and efficacious activator (agonist) of TRPML2 with EC50 of 1.24 uM and 2.38 uM for human and mouse TRPML2, respectively. |
| PC-72566 |
SH045
TRPC6 blocker
|
SH045 (SH-045, Larixyl-6-N-methylcarbamate) is a potent, selective TRPC6 antagonist (blocker) with IC50 of 63 nM. |
| PC-72564 |
CDD-1102
BRDT BD2 inhibitor
|
CDD-1102 (CDD1102) is a potent, selective second bromodomain (BD2) of BRDT and BRD4 inhibitor with IC50 of 7 and 25 nM, >1,000-fold and 300-fold selectivity over BRDT-BD1 and BRD4-BD1. |
| PC-72354 |
RGM8-51
TRPM8 antagonist
|
RGM8-51 is a β-lactam derivative, potent, selective TRPM8 antagonist with IC50 of 1.06 and 1.74 uM for rat and human TRPM8, respectively. |
| PC-72122 |
tatM2NX
TRPM2 antagonist
|
tatM2NX is a novel potent, selective, cell permeable, peptide TRPM2 channel antagonist with IC50 of 396 nM, IC90 of 2 uM (TRPM2 channel currents), prevents ligand binding and TRPM2 activation. |
| PC-72111 |
KPR-5714
TRPM8 antagonist
|
KPR-5714 (KPR5714) is a novel potent, selective TRPM8 antagonist with IC50 of 25.3 and 22.4 nM against hTRPM8 and rTRPM8, respectively. |
| PC-35612 |
AMG-333
|
AMG-333 (AMG333, AMG 333) is a novel potent, highly selective TRPM8 antagonist with IC50 of 13 nM and 20 nM for hTRPM8 and rTRPM8, respectively. |
| PC-35474 |
TRPM8 antagonist 14
|
TRPM8 antagonist 14 is a potent, selective TRPM8 antagonist with IC50 of 0.2 nM in calcium influx assays, shows no activity on TRPV1. |
| PC-35045 |
DS88790512 hydrochloride
|
DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
