| Cat. No. |
Product Name |
Information |
| PC-22127 |
SOR-C13 TFA
TRPV6 inhibitor
|
SOR-C13 TFA, a carboxy-terminal truncated peptide, is a high-affinity, selective TRPV6 calcium channel inhibitor with IC50 of 14 nM. |
| PC-22083 |
PCC0208057
TRPC6 inhibitor
|
PCC0208057 is a potent, selective TRPC6 channel inhibitor, inhibits TRPC6-mediated Ca2+ concentration increase with IC50 of 2.44 uM, binds directly to TRPC6. |
| PC-21908 |
GDC-6599
TRPA1 inhibitor
|
GDC-6599 is a potent, selective transient receptor potential ankyrin 1 (TRPA1) antagonist with IC50 of 5.3 nM (hTRPA1), exhibits TRPA1 cell potency (IC50=20 nM) in the Ca2+ influx assay in CHO cells. |
| PC-21344 |
M085
TRPC3/6/7 activator
|
M085 (TRPC3/6/7 activator 4o) is a potent and selective TRPC3/6/7 activator with EC50 of 4.66 uM, also activates hTRPC6 with EC50 of 3.8 uM. |
| PC-21342 |
Hyperforin Dicyclohexylammonium Salt
TRPC6 activator
|
Hyperforin Dicyclohexylammonium Salt is a small molecule activator of TRPC6, elevates intracellular Ca2+ concentrations by activating TRPC6 channels while not activating other TRPC isoforms. |
| PC-21131 |
AAL-149
TRPM7 inhibitor
|
AAL-149 is a non-phosphorylatable FTY720 analogue and novel TRPM7 inhibitor, inhibits IM7 in a dose-dependent manner with IC50 of 1.081 uM, shows potent anti-inflammatory effects in vivo. |
| PC-21060 |
MK6-83
TRPML1 agonist
|
MK6-83 is a specific transient receptor potential mucolipin -1 (TRPML1/MCOLN1) agonist, activates the entire endosomal TRPML1 current in DMD myocytes with EC50 of 285 nM. |
| PC-20875 |
TRPV2 inhibitor IV2-1
TRPV2 inhibitor
|
TRPV2 inhibitor IV2-1 is a novel TRPV2-selective blocker, inhibits 2-APB elicited typical inwardly rectifying TRPV2 currents with IC50 of 0.8 uM. |
| PC-20367 |
TRPM5 inhibitor NDNA
TRPM5 inhibitor
|
TRPM5 inhibitor NDNA is potent and selecive TRPM5 inhibitor, inhibits Ca2+- induced TRPM5 currents with IC50 of 2.4 nM. |
| PC-20366 |
Triphenylphosphine oxide
TRPM5 inhibitor
|
Triphenylphosphine oxide (TPPO) is a selective and potent inhibitor of TRPM5 with IC50 of 12 and 30 uM for human and murine TRPM5 heterologously expressed in HEK293 cells. |
| PC-49702 |
AZ465
TRPA1 inhibitor
|
AZ465 (AZ-465) is a potent selective TRPA1 inhibitor, potently inhibitor Zn2+ (100 μM)- and O-chlorobenzylidene malononitrile (CS) (10 nM)-induced TRPA1 activation with IC50 of 85 nM and 20 nM, respectively. |
| PC-49701 |
AMG2504
TRPA1 inhibitor
|
AMG2504 (AMG 2504) is a selective small molecule TRPA1 inhibitor, inhibits AITC-induced increase in intracellular calcium mediated by TRPA1 in CHO cells with IC50 of 35 nM. |
