| Cat. No. |
Product Name |
Information |
| PC-63429 |
JNJ-38893777 sulfate
|
JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.. |
| PC-63428 |
JNJ-38893777
|
JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.. |
| PC-63414 |
JNJ-39729209
|
JNJ-39729209 is a potent, selective TRPV1 antagonist with binding pKi of 7.8 and 7.9 for human and rat TRPV1, respectively. |
| PC-43222 |
Optovin
|
Optovin is a reversible photoactivated TRPA1 ligand that can be photoactivated by violet light, enables light-mediated neuronal excitation in treated animals with EC50 of 2 uM at 387 nm (violet), but not to 485 nm (blue), 560 nm (green) or longer wavelengths. |
| PC-43073 |
Pyr6
|
Pyr6 is a potent, selective inhibitor of TRPC3 channel with IC50 of 0.49 uM (thapsigargin-depleted native RBL-2H3 cells for SOCE). |
| PC-62914 |
JYL-1421
|
JYL-1421 (SC-0030) is a potent, competitive TRPV1 receptor antagonist with Ki of 53.5 nM, antagonizes capsaicin-induced calcium uptake with EC50 of 9.2 nM. |
| PC-62628 |
GSK205 derivative 16-8
|
GSK205 derivative 16-8 is a specific small molecule dual-inhibitor of TRPV4 and TRPA1 with IC50 of 0.45 and 0.41 uM, respectively. |
| PC-62627 |
GSK205
|
GSK205 is a selective small molecule TRPV4 channel inhibitor with IC50 of 4.19 uM. |
| PC-62012 |
ADM 12
|
ADM 12 (ADM_12. |
| PC-61767 |
JNc-440
|
JNc-440 is a small molecule that significantly and specifically strengthens the TRPV4-KCa2.3 interaction in mouse endothelial cells, but does not systemically activate TRPV4 and KCa2.3. |
| PC-61534 |
V-116517
|
V-116517 is a novel potent, selective, oral bioavailable TRPV1 antagonist with IC50 of 35.1 nM. |
| PC-61533 |
ABT-102
|
ABT-102 is a potent, highly selective, orally active TRPV1 antagonist that inhibits agonist-evoked increases in intracellular Ca(2+) levels with IC50 of 5-7 nM. |
