| Cat. No. |
Product Name |
Information |
| PC-49161 |
AS2030680
5-HT5A antagonist
|
AS2030680 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.58, 1.1 and 2.6 nM against human, rat, mouse 5-HT5A receptors, respectively. |
| PC-49006 |
LY344864
5-HT1F agonist
|
LY344864 is a potent, selective agonist of 5-HT1F receptor with Ki value of 6 nM, with little to no affinity for other serotonergic and non-serotonergic neuronal binding sites. |
| PC-47113 |
TZB-30878
5-HT1A agonist/5-HT3 antagonist
|
TZB-30878 is a potent, selective, orally bioavailable 5-HT1A agonist and 5-HT3 antagonist, selectively binds to human 5-HT1A and 5-HT) receptors with Kd values of 0.68 and 8.90 nM, respectively. |
| PC-47112 |
CSTI-300
5-HT3 agonist
|
CSTI-300 (SMP-100) is a potent, selective 5-HT3 receptor partial agonist with high affinity for human and rat 5-HT3 receptor (Ki=2.0 nM). |
| PC-38716 |
SB-699551
5-HT5A antagonist
|
SB699551 is a potent, selective 5-HT5A receptor antagonist with pKi of 8.3, >100-fold selectivity over 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors. |
| PC-73308 |
NLX-101
5-HT1A agonist
|
NLX-101 (F15599) is a potent, highly selective post-synaptic 5-HT1A receptor agonist with Ki of 3.4 nM. |
| PC-38060 |
SB 204741
5-HT2B antagonist
|
SB 204741 is a potent and selective 5-HT2B receptor antagonist (pA2=7.95). |
| PC-43515 |
SB 242084
5-HT2C antagonist
|
SB 242084 is a potent, selective, brain penetrant 5-HT2C receptor antagonist with pKi of 9.0, 100- and 158-fold selectivity over the closely related 5-HT2B and 5-HT2A subtypes. |
| PC-35004 |
PF-05212377
5-HT6 antagonist
|
PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with Ki of 0.32 nM (human 5HT6), shows potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease. |
| PC-63486 |
SB 258585 hydrochloride
5-HT6 antagonist
|
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes. |
| PC-63485 |
SB-258585
5-HT6 antagonist
|
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes. |
| PC-63483 |
SB-399885
5-HT6 antagonist
|
SB-399885 is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors. |
