| Cat. No. |
Product Name |
Information |
| PC-22540 |
YK-4-279
EWS-FLI1 inhibitor
|
YK-4-279 is a specific small molecule inhibitor of EWS-FLI1 interaction with RNA helicase A with SPR KD of 9.48 uM for EWS-FLI1, reduces EWS-FLI1 functional activity, also reduces EWS-FLI1 modulated transcription. |
| PC-22489 |
UR778Br
IQGAP1 inhibitor
|
UR778Br is a potent small molecule inhibitor of scaffolding protein IQGAP1, taregting the IQGAP1-GRD domain, selectively inhibits growth of human acute myeloid leukemia. |
| PC-22463 |
HTRA1 inhibitor 17
HTRA1 inhibitor
|
HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM. |
| PC-22462 |
HTRA1 inhibitor 10
HTRA1 inhibitor
|
HTRA1 inhibitor 10 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 10 nM. |
| PC-22460 |
DC-5163
GAPDH inhibitor
|
DC-5163 is a smal molecule glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with IC50 of 176.3 nM, inhibits glucose uptake, reduces lactic acid production, selectively inhibits cancer cell proliferation. |
| PC-22443 |
P4B
Cellulose biosynthesis inhibitor
|
P4B is a small molecule cellulose biosynthesis inhibitor of Arabidopsis (Arabidopsis thaliana) seedling growth. |
| PC-22430 |
LW-216
TrxR1 inhibitor
|
LW-216 is a novel specific small molecule thioredoxin reductase 1 (TrxR1, TXNRD1) inhibitor directly binds TrxR1 (KD of 8.8 uM in MST assays) and persistently promotes TrxR1 ubiquitination, inhibits TrxR1 expression. |
| PC-22416 |
UCF-101
Omi/HtrA2 inhibitor
|
UCF-101 is a specific inhibitor for the pro-apoptotic protease Omi/HtrA2 with IC50 of 9.5 uM, displays high selectivity over other serine proteases. |
| PC-22408 |
DUPA
Drug delivery ligand
|
DUPA is a small molecule delivery ligand with specificity for prostate-specific membrane antigen (PSMA), commonly used for selectively delivery cytotoxic agents to prostate cancer cells. |
| PC-22376 |
18:0 PEG2000 PE
|
18:0 PEG2000 PE is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells. |
| PC-22368 |
7-alpha-hydroxycholesterol
TCR inhibitor
|
7alpha-hydroxycholesterol (7a-HC) is the 7alpha-hydroxy derivative of cholesterol, is a potent inhibitor of TCR signaling and promotes membrane binding of CD3ε cytoplasmic domain. |
| PC-22352 |
Rotenone
Complex I inhibitor
|
Rotenone is a mitochondrial electron transport chain complex I inhibitor, induces apoptosis through enhancing mitochondrial reactive oxygen species production. |
