| Cat. No. |
Product Name |
Information |
| PC-62693 |
SLC25A20-IN-21
|
SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells. |
| PC-62689 |
Brequinar
DHODH inhibitor
|
Brequinar (DuP785, NSC 368390) is a potent and selective inhibitor of DHODH with IC50 of 20 nM, triggers differentiation in the ER-HoxA9, U937, and THP1 cells with an ED50 of 1 uM. |
| PC-62688 |
Perhexiline maleate
|
Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
| PC-62687 |
Perhexiline
|
Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
| PC-62671 |
MJN228
NUCB1 ligand
|
MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1). |
| PC-62658 |
Retro 2
Ricin inhibitor
|
Retro 2 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface. |
| PC-62601 |
KH 176
ROS-redox modulator
|
KH176 (Sonlicromanol) is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders. |
| PC-62590 |
YPC-21661
ZNF143 inhibitor
|
YPC-21661 is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143). |
| PC-62589 |
YPC-22026
ZNF143 inhibitor
|
YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA. |
| PC-62585 |
TRAF-STOP 6860766
|
TRAF-STOP 6860766 (SMI-6860766, SMI6860766) is a small molecule inhibitor that blocks the interaction between CD40 and TRAF6 (TRAF-STOP), while leaving CD40-TRAF2/3/5 interactions intact, thereby preserving CD40-mediated immunity. |
| PC-62577 |
Visomitin
|
Visomitin (SKQ1 bromide, PDTP) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). |
| PC-62535 |
SPL-707
SPPL2a inhibitor
|
SPL-707 (SPL707) is the first selective, orally active signal peptide peptidase-like 2a (SPPL2a) inhibitor with IC50 of 77 nM, shows 25-fold selectivity over γ-secretase and SPP. |
