| Cat. No. |
Product Name |
Information |
| PC-72347 |
JNJ-54302833
FASN inhibitor
|
JNJ-54302833 (JNJ 54302833) is a potent, selective fatty acid synthase (FASN) inhibitor with IC50 of 28 nM. |
| PC-72338 |
AGI-25696
MAT2A inhibitor
|
AGI-25696 (AGI 25696) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A, blocks the growth of MTAP-deleted tumors in vivo. |
| PC-72335 |
Ironomycin
|
Ironomycin (Ironomycin AM5) is a lysosomal iron-targeting small molecule that reduces the mitochondrial iron load, resulting in the potent disruption of mitochondrial metabolism. |
| PC-72301 |
SW2_110A
CBX8 inhibitor
|
SW2_110A (SW2-110A) is a selective, cell-permeable inhibitor of chromobox homolog protein CBX8, binds CBX8 N-terminal chromodomain (ChD) with Kd of 800 nM. |
| PC-72298 |
CBX6 inhibitor 5
CBX6 inhibitor
|
CBX6 inhibitor 5 is a selective inhibitor of methyllysine reader protein CBX6 with Kd of 0.9 uM, 90×, 20×, 18×, 6×, and 7× selective for CBX6 over CBX1/2/4/7/8, respectively. |
| PC-72285 |
TH-3021
AKR1C3 inhibitor
|
TH-3021 (SN336384) is a potent and specific inhibitor of AKR1C3 with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM). |
| PC-72270 |
SHR170008
CD73 inhibitor
|
SHR170008 is a highly potent, small molecule CD73 inhibitor with IC50 of 0.05 nM against human CD73 soluble enzyme. |
| PC-72241 |
CBLC000
FACT inhibitor
|
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |
| PC-72237 |
Myricetin
ENPP1 inhibitor
|
Myricetin (Myricetol, Myricitin) is a flavonoid compound with antioxidant properties, inhibits ENPP1 enzymatic activity with IC50 of 4.8 uM. |
| PC-72235 |
ENPP1 inhibitor QS1
ENPP1 inhibitor
|
ENPP1 inhibitor QS1 (QPS1) is a potent, selective non-competitive inhibitor of Ectonucleotide pyrophosphatase/PDE1 (NPP1, ENPP1) with Ki of 59.3 nM.
QPS1 also significantly inhibited the K121Q NPP1 gene variant with Ki of 59.2 nM. |
| PC-72175 |
OXS007417
AML differentiation inducer
|
OXS007417 (OXS 007417) is a small moelcule that induces differentiation of AML cells in vitro (CD11b increasein HL-60 cell EC50=48 nM) and shows antitumor effects in vivo. |
| PC-72155 |
L-Propargylglycine
CSE inhibitor
|
L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE). |
