| Cat. No. |
Product Name |
Information |
| PC-62234 |
Golgicide A
ArfGEF GBF1 inhibitor
|
Golgicide A is a potent, highly specific, reversible inhibitor of the cis-Golgi ArfGEF GBF1, inhibits the effect of shiga toxin on protein synthesis with IC50 of 3.3 uM. |
| PC-62221 |
ML239
|
ML239 is a selective small molecule inhibitor of breast cancer stem cells with IC50 of 1.18 uM, displays >23-fold selective inhibition of the breast CSC-like cell line over the isogenic control cell line. |
| PC-62204 |
AA 41612
OPN4 antagonist
|
AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner. |
| PC-62152 |
GGTI 2418
GGTase I inhibitor
|
GGTI 2418 (GGTI-2418, PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
| PC-62151 |
GGTI-2417
GGTase I inhibitor
|
GGTI-2417 is the methyl ester prodrug of GGTI-2418, a highly potent, competitive, and selective inhibitor of GGTase I. |
| PC-62122 |
ML382
MRGPRX1 modulator
|
ML382 is a potent, selective, positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MrgprX1) with EC50 of 190 nM in cell based Ca2+ imaging assay. |
| PC-62059 |
FSC 231
|
FSC 231 (FSC231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM. |
| PC-62048 |
MitoBloCK 6
|
MitoBloCK 6 is a small molecule mitochondrial protein import blocker that inhibits Erv1 oxidase activity. |
| PC-62047 |
MitoBloCK 1
TIM22 inhibitor
|
MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways. |
| PC-61994 |
TK216
|
TK216 is a first in class, small molecule that directly binds EWS-FLI1 inhibiting the biological activity of ETS-family transcription factor oncoproteins and is currently under clinical investigation against Ewing sarcoma.. |
| PC-61855 |
Elamipretide
|
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell type. |
| PC-61825 |
NS-3-008
|
NS-3-008 is a novel small-molecule transcriptional inhibitor of G0s2 (G0/G1 switch 2) with IC50 of 2.25 uM. |
