| Cat. No. |
Product Name |
Information |
| PC-62367 |
BRD5459
ROS inducer
|
BRD5459 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62363 |
MN30
APOBEC3G inhibitor
|
MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM. |
| PC-62361 |
Aurintricarboxylic acid
|
NSC4056 (Aurintricarboxylic acid) is a potent, bioactive inhibitor of cystathionine γ-lyase (CSE) with IC5 of 0.6 uM, also is a selective inhibitor of the TWEAK-Fn14 signaling pathway. |
| PC-62342 |
Isobutyl-deoxynyboquinone
NQO1 substrate
|
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner. |
| PC-62316 |
UM-171
|
UM-171 (UM171) is a potent agonist of human hematopoietic stem cell self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM. |
| PC-62311 |
PF-9366
MAT2A inhibitor
|
PF-9366 is a novel selective, allosteric methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM, Kd of 170 nM. |
| PC-62300 |
FEN1-IN-1
FEN1 inhibitor
|
FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM. |
| PC-62296 |
Miquelianin
|
Miquelianin (Quercetin-3-O-glucuronide) is a flavonol glucuronide that shows an antioxidant effect in human plasma. |
| PC-62259 |
Inflachromene
|
Inflachromene (ICM) is a microglial inhibitor with anti-inflammatory effects, directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. |
| PC-62252 |
WWL229
Ces3 inhibitor
|
WWL229 is a selective, distinct Carboxylesterase Ces3 inhibitor with IC50 of 1.94 uM, but not Ces1f, ABHD6, other serine hydrolases. |
| PC-62245 |
Triphenyl compound A
Pirin inhibitor
|
Triphenyl compound A (TPh A) is a small-molecule inhibitor of nuclear protein Pirin with Kd of 0.6 uM, inhibits the interaction between pirin and Bcl3 in vitro and in cells. |
| PC-62234 |
Golgicide A
ArfGEF GBF1 inhibitor
|
Golgicide A is a potent, highly specific, reversible inhibitor of the cis-Golgi ArfGEF GBF1, inhibits the effect of shiga toxin on protein synthesis with IC50 of 3.3 uM. |
