| Cat. No. |
Product Name |
Information |
| PC-60795 |
NSC 243928
|
A small molecule that potently inhibit ovarian cancer stem-like cells (CSC) growth with GI50 of 0.83 uM, which os consistent with cell death/apoptosis.. |
| PC-60714 |
PRD125
|
A potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2, ACAT2) with IC50 of 11.8 nM, >6,000-fold selectivity over ACAT1. |
| PC-60680 |
ES 936
|
A potent, specific mechanism-based human NAD(P)H: quinone oxidoreductase 1 (NQO1) inhibitor that demonstrates efficient inactivation of NQO1 at 100 nM in in cellular systems. |
| PC-60650 |
Ru360
|
A cell-permeable mitochondrial calcium uptake inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM. |
| PC-60649 |
AG311
|
A first-in-class antitumor and antimetastatic agent that induces necrosis in breast cancer tumors, inhibits inhibit mitochondria complex I activity and reduces HIF-1α stabilization. |
| PC-60631 |
OX03050
|
A novel potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM. |
| PC-60560 |
LQB-118
|
An orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo. |
| PC-60532 |
Rovazolac
|
An novel anti-inflammatory agent.. |
| PC-60531 |
IPL-576092
|
A novel orally active, anti-inflammatory compound that inhibits leukocyte infiltration and changes in lung function in response to allergen challenge. |
| PC-70226 |
RX-055
|
A tailored WOBE437-derived diazirine-containing photoaffinity probe that irreversibly blocks membrane transport of both endocannabinoids. |
| PC-60493 |
GlpG inhibitor 11
|
A potent, selective, reversible rhomboid proteases inhibitor with Ki of 45 nM for GlpG . |
| PC-60376 |
R-IMPP
|
A small molecule inhibitor of PCSK9 secretion (IC50=4.8 uM) that selectively binds to human 80S ribosome, but not E. coli, ribosomes. |
