| Cat. No. |
Product Name |
Information |
| PC-45735 |
3PO
PFKFB3 inhibitor
|
PFKFB3 inhibitor 3PO is a small-molecule, competitive inhibitor of PFKFB3 isozyme with IC50 of 23 uM. |
| PC-45763 |
Mirin
MRE11 inhibitor
|
(Z)-Mirin is a small molecule inhibitor of MRN (Mre11-Rad50-Nbs1) pathway that inhibits Mre11-associated exonuclease activity. |
| PC-42264 |
Rbin-1
|
Rbin-1 (Ribozinoindole-1) is a potent, specific and reversible inhibitor of eukaryotic ribosome biogenesis that targets the AAA+ protein Midasin (IC40=1 uM). |
| PC-42279 |
PF-1355
MPO inhibitor
|
PF-1355 is a potent, selective, orally active Myeloperoxidase (MPO) inhibitor with EC50 of 1.47 uM. |
| PC-45604 |
PF-06282999
MPO inhibitor
|
PF-06282999 is a potent, highly selective and irreversible inhibitor of myeloperoxidase (MPO) with Kinact/KI of 116000 M-1s-1. |
| PC-45038 |
ISO-1
MIF inhibitor
|
ISO-1 is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with IC50 of 7 uM. |
| PC-42227 |
ML390
DHODH inhibitor
|
ML390 is a potent DHODH inhibitor that causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) AML models (ED50=2 uM). |
| PC-42382 |
NIH-12848
PI5P4Kγ inhibitor
|
NIH-12848 is a potent and selective PI5P4Kγ inhibitor with IC50 of 1 uM, shows no significant inhibitory activity for PI5P4Kα and PI5P4Kβ (>100 uM). |
| PC-45393 |
Acebilustat
LTA4H inhibitor
|
Acebilustat (CTX-4430, EP-501) is a potent and selective leukotriene A4 hydrolase (LTA4H) inhibitor with IC50 of 64 nM for inhibition of LTB4 production in human whole blood. |
| PC-45593 |
Adjudin
|
Adjudin (AF-2364) is a potent analog of lonidamine known to disrupt germ cell adhesion, a potential candidate for male contraceptive development. |
| PC-45492 |
Ro 48-8071
|
Ro 48-8071 is a potent 2,3-oxidosqualene cyclase (OSC) inhibitor with IC50 of 6.5 nM. |
| PC-45095 |
ISA-2011B
|
ISA-2011B (ISA2011B, ISA 2011B) is a poent, selective inhibitor of Phosphatidylinositol-4-phosphate 5-kinase-α (PIP5Kα). |
