| Cat. No. |
Product Name |
Information |
| PC-60393 |
PBD-150
|
PBD150 is a potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM. |
| PC-70211 |
LY-345899
|
LY-345899 (LY345899) is a novel potent, cytoplasmic and mitochondrial methylenetetrahydrofolate dehydrogenase MTHFD1 and MTHFD2 inhibitor with IC50 of 96 nM and 663 nM, respectively. |
| PC-70176 |
MDL72527
Polyamine oxidase inhibitor
|
MDL72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively. |
| PC-70126 |
FPH2
|
FPH2 (BRD-9424) is a small molecule that promotes differentiation of iPS-derived hepatocytes, induces functional proliferation of hepatocytes in vitro, and thus expands mature human primary hepatocytes. |
| PC-70112 |
ATR-101
|
ATR-101 (PD-132301, Nevanimibe) is a selective and potent inhibitor of ACAT1 with IC50 of 52 nM. |
| PC-60222 |
CK-2127107
|
CK-2127107(CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM. |
| PC-60193 |
2-D08
UBC9 SUMOylation inhibitor
|
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation, inhibits transcriptional expressions of SUMO1/2 and Ubc9. |
| PC-60184 |
Shield-1
FKBP ligand
|
Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation. |
| PC-70005 |
Gue-1654
OXE-R inhibitor
|
Gue-1654 (GUE 1654) is a small-molecule that inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R (Oxoeicosanoid receptor) in both recombinant and human primary cells. |
| PC-70001 |
C1632
|
C1632 (Lin28-IN-1632) is a small molecule inhibitor of RNA binding protein Lin28 that blocks the Lin28/let-7 interaction, rescues let-7 processing and function in Lin28-expressing cancer cells. |
| PC-60018 |
RU-521
cGAS inhibitor
|
RU-521 (RU.521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 36.2 nM. |
| PC-42914 |
PFK-158
PFKFB3 inhibitor
|
PFK-158 is the first potent, selective and competitive small molecule inhibitor of PFKFB3 with IC50 of 137 nM, inhibits glycolysis, induces apoptosis and autophagy. |
