| Cat. No. |
Product Name |
Information |
| PC-22172 |
UCP0054278
DJ-1/PARK7 inhibitor
|
DJ-1 inhibitor comp-23 is a small molecule binding to DJ-1 (PARK7) with binding Kd of 1.33 uM, inhibits oxidative stress-induced cell death of human dopaminergic neuroblastoma cell line SH-SY5Y cells at 1 uM. |
| PC-22171 |
DJ-1 inhibitor comp-23
DJ-1/PARK7 inhibitor
|
DJ-1 inhibitor comp-23 is a small molecule binding to DJ-1 (PARK7) with binding constant (Kd) of 0.1 uM, exerts a neuroprotective effect by reducing ROS-mediated neuronal injury. |
| PC-22163 |
MO-I-1151
ASPH inhibitor
|
MO-I-1151 is a second-generation small molecule inhibitor of aspartate β-hydroxylase (ASPH), inhibits cholangiocarcinoma (CCA) cell proliferation and migration. |
| PC-22161 |
Triacsin C
ACSL inhibitor
|
Triacsin C (WS 1228A) is an inhibitor of long fatty acid acyl-CoA synthetase (ACSL) with IC50 of 6.3 μM in Raji cells, inhibits TAG accumulation into lipid droplets (LD). |
| PC-22160 |
KML110
NUCB1 ligand
|
KML110 is a selective ligand for the lipid-binding protein nucleobindin-1 (NUCB1) with IC50 of 9.6 uM. |
| PC-22154 |
OU749
GGT inhibitor
|
OU749 is a potent, species-specific inhibitor of human gamma-glutamyl transpeptidase (GGT) with Ki of 17.6 uM. |
| PC-22145 |
WX-02-23
FOXA1 ligand
|
WX-02-23 is a covalent small molecule ligand of transcription factor FOXA1 with EC50 of 2 uM in NanoBRET assay, binds cysteine (C258) and promotes the stereoselective and site-specific binding of FOXA1 to DNA. |
| PC-22137 |
HYPE inhibitor I2.10
HYPE inhibitor
|
HYPE inhibitor I2.10 is a small molecule HYPE (Huntingtin Yeast Interacting Partner E, FICD) enzyme inhibitor with IC50 of 12.1 uM, inhibits HYPE-mediated AMPylation of BiP in vtro. |
| PC-22076 |
Sulfopin
Pin1 inhibitor
|
Sulfopin is a potent, selective and covalent inhibitor of Pin1 with Ki of 17 nM in FP assay, targets Pin1's active site Cys113, blocks Myc-driven tumors. |
| PC-22060 |
Ternatin-4
eEF1A inhibitor
|
Ternatin-4 is a small molecule elongation factor-1alpha (eEF1A) inhibitor, triggers the ubiquitination and degradation of eEF1A on stalled ribosomes, targets the complex of eEF1A bound to aminoacyl-tRNAs (aa-tRNA). |
| PC-22011 |
ZZW-115 hydrochloride
NUPR1 inhibitor
|
ZZW-115 (ZZW115) hydrochloride is a potent inhibitor of NUPR1 (Kd=2.1 uM), an intrinsically disordered protein (IDP) with an entirely disordered conformation. |
| PC-21999 |
N-chloroacetyltryptamine
AANAT inhibitor
|
N-chloroacetyltryptamine is a potent in vitro and in vivo AANAT acetyltransferase inhibitor with IC50 of 5.2 uM. |
