| Cat. No. |
Product Name |
Information |
| PC-72156 |
I194496
CSE inhibitor
|
I194496 (I 194496) is a novel potent, selective inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 0.79 uM. |
| PC-72143 |
PCLX-001
pan-NMT inhibitor
|
PCLX-001 (PCLX001) is a potent, selective, orally bioavailable N-myristoyl-transferases (NMT1/2) inhibitor with IC50 of 5/8 nM, respectively. |
| PC-72128 |
GPR52 antagonist Comp-43
GPR52 antagonist
|
GPR52 antagonist Comp-43 is a highly potent and specific GPR52 antagonist with IC50 of 0.63 uM. |
| PC-72101 |
ARN19702
NAAA inhibitor
|
ARN19702 (ARN-19702) is potent, selective, orally active, reversible inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 230 nM. |
| PC-72071 |
hNPR1 inhibitor JS-11
NPR1 inhibitor
|
hNPR1 inhibitor JS-11 is a selective small-molecule inhibitor of NPPB receptor NPR1 (natriuretic peptide receptor 1), does not inhibit adenylate cyclases (ACs) family of enzymes. |
| PC-72066 |
SAR439883
PKR inhibitor
|
SAR439883 (SAR 439883) is a novel potent, selective, orally active PKR inhibitor with IC50 of 0.68/0.69 uM against hPKR/mPKR, respectively. |
| PC-72048 |
YE6144
IRF5 inhibitor
|
YE6144 (YE 6144) is a specific small molecule inhibitor of transcription factor IFN regulatory factor 5 (IRF5), selectively suppresses IRF5 activity through inhibition of IRF5 phosphorylation. |
| PC-72047 |
IRF5 inhibitor N5-1
IRF5 inhibitor
|
IRF5 inhibitor N5-1 (PRRVRLK) is a cell permeable, IRF5 peptide mimetic that selectively bind to and stabilizes the inactive IRF5 monomer with KD of 98.8 nM. |
| PC-72031 |
ARH3 inhibitor 26
ARH3 inhibitor
|
ARH3 inhibitor 26 (AI26) is a small molecule ADP-ribosylhydrolase ARH3 inhibitor that binds to the catalytic pocket of ARH3 and inhibits the enzymatic activity of ARH3 with IC50 of 2.41 uM in vitro. |
| PC-72020 |
ART558
Polθ inhibitor
|
ART558 (ART-558) is a highly potent, selective, allosteric inhibitor of the polymerase function of DNA polymerase Polθ with IC50 of 7.9 nM. |
| PC-72015 |
INI-43
Kpnβ1 inhibitor
|
INI-43 (Inhibitor of Nuclear Import-43, ZINC20547783) is a small molecule that bind nuclear import receptor Karyopherin beta 1 (Kpnβ1), inhibits Kpnβ1-mediated nuclear import with anti-cancer activity. |
| PC-38337 |
CH24H inhibitor 17
CH24H inhibitor
|
CH24H inhibitor 17 is a potent, highly selective, BBB permeable inhibitor of Cholesterol 24-hydroxylase (CH24H/CYP46A1) with IC50 of 8.5 nM. |
