| Cat. No. |
Product Name |
Information |
| PC-27832 |
Eflornithine hydrochloride hydrate
Ornithine decarboxylase inhibitor
|
Eflornithine hydrochloride hydrate (DFMO, MDL71782, RMI71782, α-difluoromethylornithine) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis. |
| PC-27826 |
DDAH1 inhibitor A8
DDAH1 inhibitor
|
DDAH1 inhibitor A8 is a small molecule inhibitor of dimethylarginine dimethylaminohydrolase 1 (DDAH1) with IC50 of 176 uM, significantly suppresses vasculogenic mimicry in TNBC cells. |
| PC-27780 |
A8535
GPR27 agonist
|
A8535 is a selective small-molecule GPR27 (SREB1) agonist. |
| PC-27778 |
Phoenixin-20
Neuropeptide
|
Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, stimulates hypothalamo-pituitary-gonadal hormones and regulates reproductive processes in mammals, promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. |
| PC-27758 |
PI5P4Kγ-IN-1
PI5P4Kγ inhibitor
|
PI5P4Kγ-IN-1 is a potent, selective and ATP-competitive chemical probe inhibitor for PI5P4Kγ with Kd of 19 nM and IC50 of 67 nM, effectively inhibits PI5P4Kγ function and activates the mTORC1 signaling pathway in cells. |
| PC-27718 |
UM-1098
Mincle agonist, Vaccine adjuvant
|
UM-1098 is a synthetic macrophage-Inducible C-type Lectin (Mincle) agonist, induces Th17, Th1, Th2 polarizing innate cytokines in mouse PBMCs, induces strong Th1 and Th17 immunity after vaccination with Mtb antigens. |
| PC-27691 |
GO1323
HsCRY1 modulator
|
GO1323 is a photopharmacological light-switchable modulator of human clock protein cryptochrome-1 (HsCRY1), selectively binds to HsCRY1, enables light-controlled manipulation of the circadian rhythm via photoisomerization. |
| PC-27642 |
DHX8-IN-1
DHX8 inhibitor
|
DHX8-IN-1 (Compound 53) is a potent, specific inhibitor of spliceosomal DEAH-box RNA helicase DHX8, inhibits DHX9 ATP-hydrolysis with IC50 of 43 nM in biochemical ADP-Glo assays, and 120 nM in RNA FA (fluorescence anisotropy) binding assays. |
| PC-27631 |
17β-HSD13-IN-1
17β-HSD13 inhibitor
|
17β-HSD13-IN-1 is a potent, selective hydroxysteroid 17-β-dehydrogenase 13 (17β-HSD13) inhibitor with cell IC50 of 14 nM, has >3000-fold seletivity over 17β-HSD1. |
| PC-27624 |
Transketolase-IN-1
Transketolase inhibitor
|
Transketolase-IN-1 (Compound 5aw) is a small molecule Transketolase (TK, EC 2.2.1.1) inhibitor, tightly binds with the enzyme At TK, exhibits potent postemergence herbicidal activity. |
| PC-27609 |
N-arachidonylglycine
GPR18 agonist, GPR92 agonist
|
N-Arachidonylglycine (NAGly, NA-Gly) is a carboxylic analog of the endocannabinoid anandamide (AEA) and endogenous ligand/agonist of GPR18 with EC50 of 44.5 nM, also is a endogenous agaonist of orphan G protein-coupled receptor GPR92 with EC50 of 4.47 uM. |
| PC-27608 |
Protoporphyrin IX disodium
CAS 50865-01-5
|
Protoporphyrin IX disodium (Proto IX, PPIX) is the branch point in chloroplast tetrapyrrole biosynthesis, also acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage, also is a dye content for fluorescence spectroscopic assays. |
