| Cat. No. |
Product Name |
Information |
| PC-21343 |
GPR101 agonist AA-14
GPR101 agonist
|
GPR101 agonist AA-14 is a specific small molecule agonist of GPR101 with EC50 of 0.37 uM, 0.88 uM and 2.14 uM in activating Gs, Gq or β-arrestin2 assays respectively. |
| PC-21339 |
Butaselen
Thioredoxin reductase inhibitor
|
Butaselen is a small molecule inhibitor of thioredoxin reductase (TrxR)/thioredoxin (Trx) with anti-tumor activity, inhibits the growth of various human cancer cell lines. |
| PC-21334 |
Aster inhibitor AI-3d
Asters inhibitor
|
Aster inhibitor AI-3d is a potent, selective small molecule inhibitor of Aster proteins (encoded by the Gramd1a-c genes) with IC50 of 0.11 μM, 0.06 μM and 0.71 uM for Aster-A, Aster-B, and Aster-C, respectively. |
| PC-21327 |
ENPP1 inhibitor 29f hydrochloride
ENPP1 inhibitor
|
ENPP1 inhibitor 29f hydrochloride is a potent, orally active inhibitor of ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), inhibits the cGAMP hydrolysis by ENPP1 in vitro with IC50 of 68 nM. |
| PC-21326 |
ENPP1 inhibitor 29f
ENPP1 inhibitor
|
ENPP1 inhibitor 29f is a potent, orally active inhibitor of ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), inhibits the cGAMP hydrolysis by ENPP1 in vitro with IC50 of 68 nM. |
| PC-21325 |
MV-658
ENPP1 inhibitor
|
MV658 a potent small molecule ENPP1 inhibitor (IC50=11 nM) as immune modulator. |
| PC-21318 |
PSB-22034
MRGPRX4 agonist
|
PSB-22034 is a potent, selective agonist of MAS-related Gq protein-coupled receptor X4 (MRGPRX4) with EC50 of 11.2 nM/32.0 nM in Ca2+ assay/β-arrestin assays (variant 83S), respectively. |
| PC-21313 |
HsClpP activator ZK53
HsClpP activator
|
HsClpP activator ZK53 is a potent, selective activator of mitochondrial caseinolytic protease P (HsClpP) with EC50 of 0.22 uM in FI-based protease activity assays, inactive toward bacterial ClpP proteins. |
| PC-21295 |
PTC-124
Readthrough promoter
|
PTC-124 (Ataluren, PTC124) is an orally bioavailable small molecule that selectively induces ribosomal readthrough of premature but not normal termination codons. |
| PC-21293 |
KRP-6
MIF inhibitor
|
KRP-6 is a potent and highly selective macrophage migration inhibitory factor (MIF) ketonase inhibitor with IC50 of 4.31 uM, significantly reduces MIF-induced neutrophil migration. |
| PC-21278 |
MSN-CD44 inhibitor 2
CD44-MSN inhibitor
|
MSN-CD44 inhibitor 2 is a small molecule FERM domain protein-protein interaction inhibitor for moesin (MSN) and CD44 with SPR KD of 0.7 uM, is a potent inhibitor of CD44-MSN interaction in live cells with IC50 of 200 nM. |
| PC-21277 |
MSN-CD44 inhibitor 1
CD44-MSN inhibitor
|
MSN-CD44 inhibitor 1 is a small molecule FERM domain protein-protein interaction inhibitor for moesin (MSN) and CD44 with SPR KD of 4.2 uM, is a potent inhibitor of CD44-MSN interaction in live cells with IC50 of 600 nM. |
