| Cat. No. |
Product Name |
Information |
| PC-49242 |
TPC2-A1-P
TPC2 agonist
|
TPC2-A1-P is a membrane permeable isoform-selective small molecule agonist agonist of two-pore channel 2 (TPC2) with EC50 of 10.5 uM in cell-based Ca2+ signals assays, mediates changes in intracellular calcium in the absence of extracellular calcium. |
| PC-49241 |
TPC2-A1-N
TPC2 agonist
|
TPC2-A1-N is a membrane permeable isoform-selective small molecule agonist agonist of two-pore channel 2 (TPC2) with EC50 of 7.8 uM in cell-based Ca2+ signals assays, mediates changes in intracellular calcium in the absence of extracellular calcium. |
| PC-49154 |
AG17724
Pin1 inhibitor
|
AG17724 (Pin1 inhibitor DMS) is a selective inhibitor of prolyl isomerase Pin1 with Ki of 0.03 uM, DMS functionalized with CAF-targeting anti-FAP-α antibodies (antiCAFs-DMS) can selectively inhibit Pin1 in CAFs, leading to efficacious but transient tumor growth inhibition. |
| PC-49007 |
KBP-066
|
KBP-066 is a potent, selective dual amylin and calcitonin receptor agonist induces an equally potent body weight loss across a broad dose range in obese rats. |
| PC-47075 |
GBT1118
Hemoglobin modifier
|
GBT1118 is a potent, orally bioavailable allosteric modifier of hemoglobin O2 affinity, binds covalently and reversibly via an imine intermediate to the NH2-terminal valine of the Hb α-chain. |
| PC-47066 |
UNC7938
|
UNC7938 (UNC10217938 ) is a small molecule that enhance the escape of oligonucleotides from intracellular membrane compartments, enhance the delivery of oligonucleotides. |
| PC-47060 |
GNF-9228
|
GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation. |
| PC-47049 |
IPHBA
IL-31 inhibitor
|
IPHBA is a small-molecule inhibitor that suppresses EPAS1-driven IL-31 induction, selectively inhibits TCR-mediated IL-31 induction in murine CD4+ T cells with IC50 of 10.6 uM. |
| PC-47047 |
FeTPPS
|
FeTPPS is a ferric porphyrin complex that causes the decomposition of peroxynitrite by catalytic isomerization to produce nitrate both in vitro and in vivo. |
| PC-47039 |
GQ352
Gαq/11 inhibitor
|
GQ352 is a small molecule Gαq/11 inhibitor, directly binds to the Gαq and inhibits the dissociation of Gαβγ heterotrimers with IC50 value of 8.9 uM. |
| PC-38907 |
2-TCPA
CAD inhibitor
|
2-TCPA is a potent, specific inhibitor of carbamoyl-phosphate synthetase, aspartate transcarbamoylase, and dihydroorotase (CAD), suppresses SARS-CoV-2 replication in Caco-2 cells with IC50 of 2.36 uM. |
| PC-38905 |
(R)-HTS-3
LPCAT3 inhibitor
|
(R)-HTS-3 is a small-molecule inhibitor of LPCAT3, an integral membrane acyltransferase in the Lands cycle responsible for generating C20:4 phospholipids. |
