| Cat. No. |
Product Name |
Information |
| PC-36121 |
DFP00173
|
DFP00173 (DFP 00173) is a potent and selective aquaporin-3 (AQP3) inhibitor with IC50 of 0.9-1.4 uM for mouse and human AQP3, with low efficacy toward mouse AQP7 and AQP9. |
| PC-36108 |
Spastazoline
Spastin inhibitor
|
Spastazoline is a potent, selective, cell-permeable, ATP-competitive inhibitor of human Spastin, inhibits the steady-state ATPase activity of the Hs-spastin with IC50 of 99 nM. |
| PC-36087 |
Berotralstat
Plasma kallikrein inhibitor
|
Berotralstat (BCX7353, BCX-7353) is a potent, highly selective, oral plasma kallikrein inhibitor. |
| PC-36076 |
FDI-6
FOXM1 inhibitor
|
FDI-6 (FOXM1 inhibitor FDI6, NCGC00099374) is a small molecule inhibitor of FOXM1 with IC50 of 22.5 uM (FOXM1 DNA binding inhibition). |
| PC-36073 |
AER-271
|
AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility. |
| PC-36053 |
PIN1 inhibitor VS10
Pin1 inhibitor
|
PIN1 inhibitor VS10 is a novel potent small molecule inhibitor of PIN1 (peptidyl-prolyl cis-trans isomerase, NIMA-interacting 1), inhibits human PIN1 isomerization with IC50 of 13.4 uM. |
| PC-36049 |
DFMO
Ornithine decarboxylase inhibitor
|
DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis. |
| PC-36047 |
AMXT-1501
Polyamine transport inhibitor
|
AMXT-1501 (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination of with DFMO. |
| PC-36024 |
CCI-006
|
CCI-006 (CCI 006) is a small molecule that inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization, and selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells (MLL-r). |
| PC-36017 |
NEO214
|
NEO214 (NEO-214) is a novel, BBB-permeable rolipram-perillyl alcohol conjugate, shows effectivity against both TMZ-sensitive and TMZ-resistant glioma cells (T98G IC50=40 uM). |
| PC-36016 |
L-291
DDAH1 inhibitor
|
L-291 (DDAH-1 inhibitor L-291) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM. |
| PC-36015 |
L-257
DDAH1 inhibitor
|
L-257 (DDAH-1 inhibitor L-257) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM, Ki of 13 uM. |
