| Cat. No. |
Product Name |
Information |
| PC-25330 |
Dioctatin
ClpP activator
|
Dioctatin is a small molecule inhibitor of aflatoxin production of Aspergillus flavus, binds to and activates mitochondrial protease ClpP of A. flavus and Escherichia coli. |
| PC-25317 |
PRDX1 inhibitor CP1
PRDX1 inhibitor
|
PRDX1 inhibitor CP1 is a potent, high-affinity small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 0.08 nM and MST binding Kd of 0.06 nM. |
| PC-25316 |
Conoidin A
PRDX1 inhibitor, TgPrxII inhibitor
|
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties, covalently binds to the peroxidatic Cys47 of TgPrxII and inhibits its hyperperoxidation activity with IC50 of 23 uM, also is a small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 14.8 uM. |
| PC-25315 |
PRDX1 inhibitor 7e
PRDX1 inhibitor
|
PRDX1 inhibitor 7e (PRDX1-IN-1) is a potent peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 164 nM. |
| PC-25314 |
UNI110
CAS 2648334-60-3
|
UNI110 is a potent small molecule inhibitor of mismatch repair (MMR)-deficient cancer cells, selectively kills MutSa deficient cells with IC50 of 25.05 µM in HEC59 cells and 56.57 µM in HEC59-2 cells. |
| PC-25283 |
KG022
hairpin RNAs binder
|
KG022 is a fluoroquinolone derivative, binds specifically to the bulge-out region of hairpin RNAs, binds to RNA-C and RNA-G stronger than RNA-A and RNA-U based on the exchange rates. |
| PC-25260 |
IPR-3242
uPAR-uPA inhibitor
|
IPR-3242 is a small molecule inhibitor of the uPAR·uPA protein-protein interaction, inhibits the uPAR·uPAATF interaction with IC50 of 8.6 uM. |
| PC-25259 |
IPR-803
uPAR-uPA inhibitor
|
IPR-803 is a small molecule inhibitor of the uPAR·uPA protein-protein interaction, binds directly to uPAR with sub-micromolar affinity of 0.2 uM. |
| PC-25258 |
IPR-456
uPAR-uPA inhibitor
|
IPR-456 is a small molecule inhibitor of the uPAR·uPA protein-protein interaction, binds to uPAR with Kd of 310 nM, inhibits uPA binding to uPAR of breast MDA-MB-231 tumor cells with IC50 of 8 uM. |
| PC-25256 |
Profilin-1 inhibitor UP-6
Profilin-1 inhibitor
|
Profilin-1 inhibitor UP-6 is a specific small molecule inhibitor of actin-binding protein profilin-1 (Pfn1), inhibits Pfn1-actin interaction and shows potent anti-angiogenic activity in vitro and in vivo. |
| PC-25255 |
Pfn1-actin interaction inhibitor C74
Profilin-1 inhibitor
|
Pfn1-actin interaction inhibitor C74 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, reduces RCC cell proliferation in vitro and tumor growth in vivo. |
| PC-25254 |
Pfn1-actin interaction inhibitor C2
Profilin-1 inhibitor
|
Pfn1-actin interaction inhibitor C2 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, inhibits the angiogenic ability of vascular endothelial cells (ECs), affects the actin cytoskeleton, migration, and proliferation of Ecs. |
