| Cat. No. |
Product Name |
Information |
| PC-38227 |
DCLK1-IN-1
DCLK1 inhibitor
|
DCLK1-IN-1 is the first potent, selective inhibitor of the DCLK1 and DCLK2 kinases with IC50 of 9.5 nM and 31 nM in binding assays, respectively. |
| PC-38226 |
TH1760
NUDT15 inhibitor
|
TH1760 (TH 1760) is a first-in-class, potent, selective, cell-active NUDT15 inhibitor with IC50 of 25 nM. |
| PC-38225 |
TH7285
|
TH7285 is the negative control compound (IC50>100 uM) of TH1760, a potent, selective NUDT15 inhibitor. |
| PC-38224 |
Cas9 inhibitor 85
Cas9 inhibitor
|
Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.. |
| PC-38215 |
UNC10245350
|
UNC10245351 is a N-terminal HIV Tat conjugate to UNC10245092, a CIB1 peptide inhibitor (Kd=192 nM), cell-penetrating. |
| PC-38214 |
H3B-120
CPS1 inhibitor
|
H3B-120 (H3B 120) is a selective allosteric inhibitor of Carbamoyl phosphate synthetase 1 (CPS1) with Ki of 1.4 uM, does not bind to CPS2. |
| PC-38213 |
H3B-616
CPS1 inhibitor
|
H3B-616 (H3B 616) is a potent, selective allosteric inhibitor of CPS1 with IC50 of 66 nM, demonstrates no appreciable inhibition of CPS2 (IC50>100 uM). |
| PC-38212 |
KLK6 inhibitor 32
KLK6 inhibitor
|
KLK6 inhibitor 32 is a potent and selective inhibitor of kallikrein‐related peptidase 6 (KLK6) with IC50 of 2.5 nM, high selectivity against KLK7, KLK8, Trypsin, Thrombin.. |
| PC-38211 |
KLK6 inhibitor 42
KLK6 inhibitor
|
KLK6 inhibitor 42 is a first-in-class inhibitor of kallikrein‐related peptidase 6 (KLK6, IC50=1.57 uM) that promote the differentiation of OPCs into mature oligodendrocytes in vitro.. |
| PC-38207 |
COUP-TFII inhibitor CIA1
COUP-TFII inhibitor
|
CIA1 (COUP-TFII inhibitor A1) is a potent and specific inhibitor of COUP-TFII activity, inhibits COUP-TFII–driven NGFIA reporter expression with IC50 of 3.2 uM, disturbs COUP-TFII binding to FOXA1 to regulate target gene expression. |
| PC-38205 |
CYD19
Snail inhibitor
|
Snail inhibitor CYD19 (CYD19) is a small-molecule compound that binds to the zinc finger transcription factor Snail (Kd=0.18 uM), and disrupts Snail interaction with CBP/p300. |
| PC-38202 |
AE 51310
OPN4 antagonist
|
AE 51310 is a small-molecule inhibitor of Opsin 4/melanopsin (OPN4), has antitumor potential in patient-derived xenograft (PDX) tumors in mice.. |
