| Cat. No. |
Product Name |
Information |
| PC-70335 |
TRAF-STOP 6877002
CD40-TRAF6 inhibitor
|
TRAF-STOP 6877002 (SMI-6877002) is a small molecule inhibitor that blocks the interaction between CD40 and TRAF6 (TRAF-STOP), while leaving CD40-TRAF2/3/5 interactions intact, thereby preserving CD40-mediated immunity. |
| PC-70334 |
SC57461A
LTA4H inhibitor
|
SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM. |
| PC-70333 |
ARM-1
LTA4H inhibitor
|
ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM. |
| PC-70315 |
Endosidin-2
EXO70 inhibitor
|
Endosidin-2 is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking. |
| PC-70313 |
SI-2
|
SI-2 (EPH-116) is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. |
| PC-70287 |
PDZ1i
MDA-9/Syntenin inhibitor
|
PDZ1i (113B7) is a specific inhibitor of MDA-9/Syntenin activity that inhibits MDA-9/Syntenin binding to EGFRvIII. |
| PC-70286 |
FD-44
|
FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model. |
| PC-70281 |
CBR-096-4
|
CBR-096-4 is a derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues. |
| PC-61205 |
XEN 602
DMT1 inhibitor
|
XEN 602 (XEN602) is a potent, specific divalent metal transporter 1 (DMT1) inhibitor that inhibits Mn incorporation in HEK293 cells with IC50 of 0.3 nM. |
| PC-61190 |
CCT 365623 hydrochloride
Lysyl oxidase inhibitor
|
CCT 365623 (CCT365623) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
| PC-61189 |
CCT 365623
Lysyl oxidase inhibitor
|
CCT 365623(CCT365623, CCT-365623) is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
| PC-61188 |
Barbadin
|
Barbadin is a small molecule that selectively inhibits the β-arrestin/β2-adaptin interaction (IC50=19.1/15.6 uM for β-arrestin1/2) without effect on the formation of receptor/β-arrestin complexes. |
