| Cat. No. |
Product Name |
Information |
| PC-20505 |
MEISi-2
MEIS1 inhibitor
|
MEISi-2 (MEIS inhibitor 2) is a specific small molecule inhibitor of MEIS1 (Meis1), significantly inhibits MEIS1 protein activity in MEIS-luc reporter assays at 0.1 uM, modulates hematopoietic stem cell (HSC) activity. |
| PC-20504 |
MEISi-1
MEIS1 inhibitor
|
MEISi-1 (MEIS inhibitor 1) is a specific small molecule inhibitor of MEIS1 (Meis1), significantly inhibits MEIS1 protein activity in MEIS-luc reporter assays at 0.1 uM, modulates hematopoietic stem cell (HSC) activity. |
| PC-20489 |
OSM-SMI-10B
Oncostatin M inhibitor
|
OSM-SMI-10B (SMI-10B) is a first-in-class small molecule inhibitor binds to oncostatin M (OSM) with Kd of 13.6 uM, significantly reduces OSM-induced STAT3 phosphorylation in cancer cells. |
| PC-20482 |
K786-4469
Anoctamin 1 inhibitor
|
K786-4469 is a small molecule inhibitor of anoctamin 1 (ANO1), suppresses cancer metastasis in vitro and in vivo. |
| PC-20454 |
Caf1 inhibitor 8j
|
Caf1 inhibitor 8j is a potent, selective inhibitor of human poly(A)-selective ribonuclease Caf1 with IC50 of 0.59 uM, 40-fold selectivity over the related deadenylase PARN. |
| PC-20420 |
SC144
gp130 inhibitor
|
SC144 (SC-144) is the first-in-class orally active small-molecule gp130 inhibitor with a broad-spectrum anticancer activity. |
| PC-20400 |
DHAB
ADPR-cyclase inhibitor
|
DHAB is a potent, specific small molecule inhibitor of kidney ADPR-cyclase with IC50 of 2.5 nM, does not inhibit CD38, spleen, heart or brain ADPR-cyclase activity in vitro. |
| PC-20399 |
SAN4825
ADPR-cyclase inhibitor
|
SAN4825 is a selective small-molecule inhibitor of cardiac ADP-ribosyl cyclase (ADPR cyclase) with IC50 of 0.13 uM. |
| PC-20389 |
Dantrolene
|
Dantrolene (F368) is a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase with Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. |
| PC-20384 |
Sulfosuccinimidyl oleate sodium
CD36 inhibitor
|
Sulfosuccinimidyl oleate sodium (SSO) is an irreversible inhibitor of the fatty acid translocase CD36, inhibits fatty acid transport (FAT) into cells. |
| PC-20371 |
PIP5K inhibitor 20
|
PIP5K inhibitor 20 is a potent, selective pan-PIP5K inhibitor with IC5 values of 58, 46 and 39 nM for PIP5Kα, PIP5Kβ and PIP5Kγ, respectively. |
| PC-20346 |
SYNTi
|
SYNTi is a small molecule PDZ domain inhibitor targeting the syndecan/syntenin protein-protein interaction with IC50 of 400 nM. |
