| Cat. No. |
Product Name |
Information |
| PC-21998 |
AANAT inhibitor 1
AANAT inhibitor
|
AANAT inhibitor 1 is a highly potent arylalkylamine N-acetyltransferase (AANAT) inhibitor with IC50 of 500 nM, covalently reacts with AANAT product CoASH. |
| PC-21989 |
BRD1732
|
BRD1732 is an ubiquitinated bifunctional small molecule that could be directly ubiquitinated in cells, resulting in dramatic accumulation of inactive ubiquitin monomers and polyubiquitin chains causing broad inhibition of the ubiquitin-proteasome system. |
| PC-21975 |
Canlitinib
|
Canlitinib is a tyrosine kinase inhibitor, extracted from patent WO2018072614 (IV-2). |
| PC-21972 |
Bezisterim
|
Bezisterim (HE3286) is an orally bioavailable synthetic analogue of an active DHEA metabolite, displays both glucose-lowering and cholesterol-lowering effects. |
| PC-21959 |
Tunicamycin
N-glycosylation inhibitor
|
Tunicamycin is a homologous nucleoside antibiotic and GlcNAc phosphotransferase (GPT) inhibitor, inhibits N-glycosylation and induces ER-stress, inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity. |
| PC-21958 |
Thapsigargin
ER stress inducer
|
Thapsigargin is a natural small molecule endoplasmic reticulum (ER) stress inducer and microsomal Ca2+-ATPase inhibitor, also efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication. |
| PC-21945 |
EBP inhibitor 11
EBP inhibitor
|
EBP inhibitor 11 is a potent, selective, brain-penetrant, orally bioavailable inhibitor of emopamil binding protein (EBP) with mGCMS zymo EC50 of 8 nM, and OPC differentiation EC50 of 44 nM. |
| PC-21942 |
PU.1 inhibitor A11
PU.1 inhibitor
|
PU.1 inhibitor A11 is a small molecule inhibitor of transcription factor PU.1 with EC50 of 2.5 nM in reporter assays, moderates the inflammatory response in human iPSC-derived microglia-like cells (iMGLs) by downregulating inflammatory PU.1-target gene expression without affecting hematopoiesis. |
| PC-21926 |
AZ9567
MAT2A inhibitor
|
AZ9567 is a potent, selective methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 1 nM, selectively targets MTAP-deficient cancer cells. |
| PC-21924 |
MAGMAS inhibitor BT9
MAGMAS inhibitor
|
MAGMAS inhibitor BT9 is a small molecule MAGMAS (mitochondria associated, granulocyte-macrophage colony stimulating factor signaling molecule) inhibitor with binding Kd of 33 uM. |
| PC-21923 |
Epoxykynin
sEH inhibitor
|
Epoxykynin is a potent, selective soluble epoxide hydrolase (sEH) with IC50 of 36 nM, inhibits the hydrolase activity of sEH and modulates kynurenine pathway. |
| PC-21895 |
MAT2A inhibitor 29
MAT2A inhibitor
|
MAT2A inhibitor 29 (AZ-29) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 27.9 nM. |
