| Cat. No. |
Product Name |
Information |
| PC-35107 |
BTZO-1
MIF activator
|
BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression. |
| PC-35092 |
JI130
|
JI130 (JI-130) is a specific Hse1 inhibitor that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone, blocks Hes1-mediated transcriptional repression. |
| PC-35091 |
JI051
Hes1 inhibitor
|
JI051(JI-051) is a specific compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone, blocks Hes1-mediated transcriptional repression. |
| PC-63570 |
Siomycin A
FOXM1 inhibitor
|
Siomycin A (NSC 285116) is an antibiotic thiazole inhibitor of the oncogenic transcription factor FOXM1, down-regulates the transcriptional activity as well as the protein and mRNA abundance of FoxM1. |
| PC-63471 |
CD38 inhibitor 78c
CD38 inhibitor
|
CD38 inhibitor 78c is a potent, specific, reversible CD38 inhibitor with Ki of 14.5 nM for recombinant human CD38. |
| PC-63456 |
ERGi-USU
|
NSC139021 (NSC 139021, ERGi-USU) is a specific RIOK2 inhibitor, selectively inhibits ERG-positive cancer cell growth, directly binds (Kd=200 nM) and inhibits RIOK2 protein with IC50 of 220 nM (VCaP) and 360 nM (COLO320). |
| PC-63447 |
Syn-TEF1
|
Syn-TEF1 is a molecule actively enables transcription across repressive GAA repeats that silence frataxin expression in Friedreich's ataxia, license transcription elongation at targeted genomic loci. |
| PC-63409 |
JNJ-26993135
LTA4H inhibitor
|
JNJ-26993135 is a potent, selective leukotriene A4 hydrolase (LTA4H) inhibitor, inhibits both the epoxide hydrolase and aminopeptidase activities of recombinant human LTA4H with IC50 of 10 nM. |
| PC-63355 |
Compound-326
D5D/FADS1 inhibitor
|
Compound-326 (D5D inhibitor 326, D5D-IN-326) is apotent, selective, orally active delta-5 desaturase (D5D, FADS1/Fatty Acid Desaturase 1) with IC50 of 72 and 22 nM for rat and human D5D, respectively. |
| PC-63313 |
IP6K1 inhibitor TNP
IP6K inhibitor
|
IP6K1 inhibitor TNP is a potent, selective inositol hexakisphosphate kinase IP6K with IC50 of 0.47 uM (IP6K1), does not inhibit either human or yeast Vip/PPIP5K. |
| PC-63262 |
(R)-HZ05
DHODH inhibitor
|
(R)-HZ05 is a potent DHODH inhibitor with IC50 of 11 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo.. |
| PC-63261 |
HZ05
DHODH inhibitor
|
HZ05 is a potent DHODH inhibitor with IC50 of 32 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo.. |
