| Cat. No. |
Product Name |
Information |
| PC-25014 |
MG-257
Galectin-3/TREM2 inhibitor
|
MG-257 is a small molecule ligand of galectin-3, impedes interaction between TREM2 and galectin-3 with IC50 of 91 nM in TR-FRET assays, attenuates TREM2 signaling. |
| PC-25013 |
TREM2 agonist C1
TREM2 agonist
|
TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays. |
| PC-25011 |
YT-II-100
CPSF3 inhibitor
|
YT-II-100 is a novel small molecule inhibitor of Cleavage and Polyadenylation Specific Factor 3 (CPSF3), increases the global abundance of R-loops. |
| PC-25008 |
Veonetinib
Tyrosine kinase inhibitor
|
Veonetinib (Example 3) is an effective inhibitor of tyrosine kinase, exhibits IC50 values of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively. |
| PC-24973 |
Progerinin
Lamin A-Progerin inhibitor
|
Progerinin (SLC-D011) is a specific, small molecule binding inhibitor of lamin A and progerin, reduces progerin expression and improves aging phenotypes in vitro and in vivo HGPS models. |
| PC-24963 |
Navepdekinra
IL-17A inhibitor
|
Navepdekinra (DC-806, S 011806, LY4100504) is a potent, oral, next-generation interleukin-17A (IL-17A) inhibitor. |
| PC-24962 |
KL1333
NAD+ modulator, NQO1 substrate
|
KL1333 (Napazimone) is an orally available, small molecule NAD+ modulator, reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. |
| PC-24950 |
Eloralintide sodium
Amylin receptor agonist
|
Eloralintide sodium (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24949 |
Eloralintide
Amylin receptor agonist
|
Eloralintide (LY3841136) is a selective amylin mimetic and long acting amylin receptor (AMYR) agonist, binds to amylin receptors with high selectivity from calcitonin receptors. |
| PC-24943 |
LCKLSL hydrochloride
ANXA2 inhibitor
|
LCKLSL hydrochloride (Leu-Cys-Lys-Leu-Ser-Leu) is a potent, specific hexapeptide competitive inhibitor of Annexin A2 (AnxA2), inhibits tissue plasminogen activator (tPA)-binding capacity with IC50 of 11 uM. |
| PC-24942 |
LCKLSL
ANXA2 inhibitor
|
LCKLSL (Leu-Cys-Lys-Leu-Ser-Leu) is a potent, specific hexapeptide competitive inhibitor of Annexin A2 (AnxA2), inhibits tissue plasminogen activator (tPA)-binding capacity with IC50 of 11 uM. |
| PC-24926 |
Opa1 inhibitor 0
Opa1 inhibitor
|
Opa1 inhibitor 0 (Opitor-0) is a reversible, noncompetitive inhibitor of mitochondrial dynamin-related protein Optic Atrophy 1 (OPA1) with IC50 of 3.0 uM against GTPase activity, effectively induces mitochondrial fragmentation in both human and mouse cells. |
