Cat. No. |
Product Name |
Information |
PC-49816 |
SS-1-148
hOAT inhibitor
|
SS-1-148 is a potent, selective inhibitor of human ornithine δ-aminotransferase (hOAT) with Ki of 60 uM, shows excellent selectivity over other related aminotransferases (e.g., GABA-AT). |
PC-49815 |
OV329
GABA-AT inhibitor
|
OV329 (OV 329) is a highly potent inactivator of gamma-aminobutyric acid aminotransferase (GABA-AT) with Ki of 9.69 uM. |
PC-49807 |
Muramyl Dipeptide
|
Muramyl Dipeptide is a naturally occurring component of bacterial cell walls that has the capacity to activate macrophages, is an immunological adjuvant. |
PC-49803 |
ClpP agonist TR-65
|
ClpP agonist TR-65 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.3 nM. |
PC-49802 |
ClpP agonist TR-57
|
ClpP agonist TR-57 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 15.5 nM. |
PC-49801 |
ClpP agonist TR-27
|
ClpP agonist TR-27 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.7 nM. |
PC-49767 |
CNS-11g
Alpha-synuclein inhibitor
|
CNS-11g is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
PC-49766 |
CNS-11
Alpha-synuclein inhibitor
|
CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
PC-49756 |
NB-598 maleate
Squalene epoxidase inhibitor
|
NB-598 (NB598) is a potent competitive inhibitor of squalene epoxidase (SQLE, SE, squalene monooxygenase) with IC50 of 4.4 nM (rat SE), inhibits microsomal squalene epoxidase from dog liver and Hep G2 cells with IC50 of 2.0 and 0.75 nM, respectively. |
PC-49755 |
MM0299 analog 13
Lanosterol synthase inhibitor
|
MM0299 analog 13 (MM 0299 derivative 13) is a potent, selective, orally bioavailable, brain-penetrant inhibitor of lanosterol synthase (LSS, competition EC50=28.7 nM) with anti-proliferative activity. |
PC-49754 |
MM0299
Lanosterol synthase inhibitor
|
MM0299 (MM 0299) is a potent, selective inhibitor of lanosterol synthase (LSS, competition EC50=1.97 nM) with anti-proliferative activity, inhibits Mut6 cell growth (IC50=18.2 nM) and induces the synthesis of 24(S),25-epoxycholesterol (EPC). |
PC-49751 |
Cl-NIO
DDAH-1 inhibitor
|
Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase. |