| Cat. No. |
Product Name |
Information |
| PC-61182 |
KPT-6566
PIN1 inhibitor
|
KPT-6566 (KPT6566) is a potent, specific and covalent inhibitor of the prolyl isomerase PIN1 with Ki of 625.2 nM, IC50 of 0.64 uM. |
| PC-61128 |
PAT-1251
LOXL2 inhibitor
|
Lenumlostat (GB2064, PAT1251) is a potent, selective and orally bioavailable lysyl oxidase-like 2 (LOXL2) inhibitor with IC50 of 0.71 uM in human whole blood assays, with high selectivity over LOX (400-fold) and other amine oxidases. |
| PC-61039 |
Lapaquistat
|
Lapaquistat (TAK-475) is a novel potent, competitive, orally active squalene synthase inhibitor with IC50 of 78 nM. |
| PC-61037 |
T-3364366
D5D/FADS1 inhibitor
|
T-3364366 is a potent, selective and orally available inhibitor of delta-5 desaturase (D5D) with Ki of <2.7 nM and IC50 of 19 nM, with excellent selectivity over D6D and SCD. |
| PC-61013 |
DS79182026
|
DS79182026 (DS-79182026) is a potent, orally active hepcidin production inhibitor with IC50 of 39 nM, with low kinase inhibitory activity. |
| PC-61011 |
DS-1040 tosylate hydrate
|
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
| PC-61010 |
DS-1040 tosylate
|
DS-1040 tosylate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
| PC-61009 |
DS-1040
|
DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
| PC-60998 |
ASP9521
|
ASP9521(ASP-9521) is a potent, selective, orally bioavailable inhibitor of Aldo-keto reductase 1C3 (17βHSD5, AKR1C3) with IC50 of 11 nM and 49 nM for recombinant human or cynomolgus monkey AKR1C3, respectively. |
| PC-60959 |
NGI-1
OST inhibitor
|
NGI-1 (ML414) is a potent, cell-permeable oligosaccharyltransferase (OST) inhibitor with IC50 of 1.1 uM. |
| PC-60880 |
ZINC 39395747
CYB5R3 inhibitor
|
ZINC 39395747 is a novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM. |
| PC-50007 |
BRD10330
|
BRD10330 (BRD-10330) is a small molecule that upregulates IL-10 production in BMDCs. |
