| Cat. No. |
Product Name |
Information |
| PC-21175 |
GPR54 antagonist 15a
GPR54 inhibitor
|
GPR54 antagonist 15a is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.6/15 nM (human/rat GPR54) in receptor binding assays. |
| PC-21149 |
25-Hydroxycholesterol
SREBP-1 inhibitor
|
25-Hydroxycholesterol (25-HC) is a specific sterol regulatory element-binding proteins (SREBP-1) inhibitor, decreases SREBP-1 protein level in cells. |
| PC-21144 |
4-ABAH
MPO inhibitor
|
4-ABAH is a specific irreversible inhibitor of myeloperoxidase (MPO) activity. |
| PC-21028 |
PIP-199
RMI-MM2 inhibitor
|
PIP-199 is a small-molecule inhibitor of the Fanconi anemia complementation group M-RecQ-mediated genome instability protein (FANCM-RMI) protein-protein interaction, inhibits RMI core complex with Kd of 3.4 uM. |
| PC-21018 |
Mito-LND
OxPhos inhibitor
|
Mito-LND (Mito-lonidamine) is a tumor-selective inhibitor of oxidative phosphorylation with IC50 of 1.2 and 2.4 uM for mitochondrial complexes I and II, respectively, impacts the activity of mitochondrial complexes, ROS generation and peroxiredoxin oxidation. |
| PC-21007 |
NPAS3 inhibitor 6
NPAS3 inhibitor
|
NPAS3 inhibitor 6 is a highly potent neuronal PAS domain protein 3 (NPAS3) inhibitor with IC50 of 282 nM, blocks the NPAS3-ARNT heterodimerization by covalently conjugating ARNT Cys336 residue. |
| PC-21001 |
HYGIC
|
HYGIC is a small molecule that simultaneously induces hypocotyl elongation and thickening via the ethylene signaling pathway activated by endogenous ethylene. |
| PC-20964 |
DX2-201
OXPHOS complex I inhibitor
|
DX2-201 is a potent and selective oxidative phosphorylation (OXPHOS) complex I inhibitor with IC50 of 312 nM in NAD/NADH assays. |
| PC-20937 |
NV930
FTSJ1 inhibitor
|
NV930 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo. |
| PC-20935 |
NV914
FTSJ1 inhibitor
|
NV914 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo. |
| PC-20931 |
CIN-16645
|
CIN-16645 (LP-01) is an ionizable cationic amino lipid used in combination with other lipids in the formation of lipid nanoparticles (LNPs) to deliver single-guide RNA (sgRNA) targeting MHC class II transactivator (CIITA) in T cells. |
| PC-20930 |
DLin-MC2-DMA
|
DLin-MC2-DMA is an ionizable lipid used for development of lipidoid nanoparticles for siRNA, mRNA, and vaccine delivery. |
