| Cat. No. |
Product Name |
Information |
| PC-20062 |
SBL-105
DHODH inhibitor
|
SBL-105 (SBL105) is a potent, selective DHODH inhibitor with IC50 of 48.48 nM (rh DHODH). |
| PC-20061 |
Nizubaglustat
GCS inhibitor
|
Nizubaglustat is a potent, selective inhibitor of glucosylceramide synthase (GCS) with IC50 of 25 nM, inhibits acid glucosylceramidase (GBA1) and neutral glucosylceramidase (GBA2) with IC50 of 200 and 0.08 nM, respectively. |
| PC-20052 |
KISS1-305
KISS1R agonist
|
KISS1-305 is a potent, selective KiSS1-derived peptide receptor (KISS1R) agonist with cellular IC50 of 8.94 nM. |
| PC-20028 |
Ederimotide
|
Ederimotide (WT1-A1) is a synthetic peptide derived from nonamer sequences of the Wilms tumor protein 1 (WT1), increases human T-cell responses and shows potential as cancer vaccine. |
| PC-20027 |
Dibutepinephrine
|
Dibutepinephrine is a sympathomimetic compound. |
| PC-20014 |
IGGi-11me
GIV-Gαi inhibitor
|
IGGi-11me is a specific, cell-active small molecule inhibitor of GIV-dependent G-protein cell signaling, binds to G-protein α-subunits, specifically disrupts their engagement with GIV/Girdin. |
| PC-20013 |
IGGi-11
GIV-Gαi inhibitor
|
IGGi-11 is a first-in-class small molecule inhibitor of non-canonical activation of heterotrimeric G-protein signaling, binds to G-protein α-subunits (Gαi, Gαi3 ITC Kd=4 uM), specifically disrupts their engagement with GIV/Girdin. |
| PC-20012 |
GCN2iB
GCN2 inhibitor
|
GCN2iB (GCN2 inhibitor) is a potent, selective and ATP-competitive GCN2 inhibitor with IC50 of 2.4 nM. |
| PC-49858 |
Tafamidis
Transthyretin stabilizer
|
Tafamidis is a potent and selective transthyretin (TTR) kinetic stabilizer with EC50 of 2.7-3.2 uM for WT-TTR and mutant tetramers V30M-TTR, V122I-TTR, inhibits amyloidogenesis. |
| PC-49857 |
AG10
Transthyretin stabilizer
|
AG10 is a potent and selective kinetic stabilizer and ligand of transthyretin (TTR) ligand with apparent binding constant (Kapp) of 193 nM for WT-TTR. |
| PC-49851 |
Nalacin
group II GH3 inhibitor
|
Nalacina is a small molecule that partially mimicks the effects of auxin and potent inhibitor of indole-3-acetic acid (IAA) conjugation mediated by group II GH3 (Gretchen Hagen 3) in vascular plants, inhibits Gretchen Hagen 3 (GH3) acyl acid amido synthetases. |
| PC-49847 |
EP055
Sperm EPPIN inhibitor
|
EP055 (EP-055) is a small molecule that targets EPPIN on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
