| Cat. No. |
Product Name |
Information |
| PC-25357 |
Avicularin
FOXM1 inhibitor
|
Avicularin is a Chinese herbal medicine with anti-inflammatory and antioxidative effects, reduces cell viability and induces caspase-dependent apoptosis in NSCLC cells by facilitating USP7-dependent degradation of FOXM1. |
| PC-25349 |
hClpP inhibitor TG42
hClpP inhibitor
|
hClpP inhibitor TG42 is a potent and selective inhibitor of hClpP with IC50 of 0.39 uM, efficiently blocks proteolysis. |
| PC-25348 |
AV167
ClpP inhibitor
|
AV167 is a potent, small molecule inhibitor of Caseinolytic protease P (ClpP) with IC50 of 1.54 uM. |
| PC-25347 |
BC8a
hClpP inhibitor
|
BC8a (ClpP inhibitor 8a) is a potent inhibitor of hClpP with IC50 of 10.2 uM, inhibits hClpP peptidase activity, also inhibits the holoenzyme hClpXP. |
| PC-25340 |
Imifoplatin
CAS 1339960-28-9
|
Imifoplatin (PT-112) is the first pyrophosphate-platinum conjugate, causes immunogenic cell death in experimental models, is an immunogenic cell death (ICD)-inducing small molecule, inhibits ribosome biogenesis and causes organelle stresses, leading to selective ICD in cancer cells. |
| PC-25339 |
CQ3196
RIOK2 inhibitor
|
CQ3196 is a potent and orally bioavailable RIO kinase 2 (RIOK2) inhibitor with binding Kd of 14 nM, suppresses RIOK2 ATPase activity in vitro with IC50 of 72 nM in an ADP-Glo kinase assays. |
| PC-25330 |
Dioctatin
ClpP activator
|
Dioctatin is a small molecule inhibitor of aflatoxin production of Aspergillus flavus, binds to and activates mitochondrial protease ClpP of A. flavus and Escherichia coli. |
| PC-25317 |
PRDX1 inhibitor CP1
PRDX1 inhibitor
|
PRDX1 inhibitor CP1 is a potent, high-affinity small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 0.08 nM and MST binding Kd of 0.06 nM. |
| PC-25316 |
Conoidin A
PRDX1 inhibitor, TgPrxII inhibitor
|
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties, covalently binds to the peroxidatic Cys47 of TgPrxII and inhibits its hyperperoxidation activity with IC50 of 23 uM, also is a small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 14.8 uM. |
| PC-25315 |
PRDX1 inhibitor 7e
PRDX1 inhibitor
|
PRDX1 inhibitor 7e (PRDX1-IN-1) is a potent peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 164 nM. |
| PC-25314 |
UNI110
CAS 2648334-60-3
|
UNI110 is a potent small molecule inhibitor of mismatch repair (MMR)-deficient cancer cells, selectively kills MutSa deficient cells with IC50 of 25.05 µM in HEC59 cells and 56.57 µM in HEC59-2 cells. |
| PC-25307 |
SyntOFF
Syntenin inhibitor
|
SyntOFF is a specific small molecule inhibitor of syntenin with IC50 of 37 uM in HTRF assays, targets the PDZ2 domain of syntenin. |
