| Cat. No. |
Product Name |
Information |
| PC-38337 |
CH24H inhibitor 17
CH24H inhibitor
|
CH24H inhibitor 17 is a potent, highly selective, BBB permeable inhibitor of Cholesterol 24-hydroxylase (CH24H/CYP46A1) with IC50 of 8.5 nM. |
| PC-38323 |
DMT1 inhibitor 18g
DMT1 inhibitor
|
DMT1 inhibitor 18g is the most potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 20 nM in calcein fluorescence assay.. |
| PC-38320 |
msR4M-L1
MIF inhibitor
|
msR4M-L1 is a chemokine-selective CXCR4 ectodomain mimic that selectively binds to MIF (KD<40 nM) but not CXCL12 (>140-fold selectivity). |
| PC-38301 |
PRGL493
ACSL4 inhibitor
|
PRGL493 (PRGL 493) is a potent selective inhibitor of Acyl-CoA synthetase 4 (ACSL4). |
| PC-38288 |
Apostatin-1
TRADD inhibitor
|
Apostatin-1 is a small molecule that binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). |
| PC-38287 |
ICCB-19
TRADD inhibitor
|
ICCB-19 is a small molecule that binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). |
| PC-38284 |
LDC7559
PFKL activator
|
LDC7559 is a small molecule that efficiently blocks NET formation and GSDMD-mediated pyroptotic cell death in human cells, also is an inhibitor of NOX2-dependent NETosis. |
| PC-38283 |
PFKL activator NA-11
PFKL activator
|
PFKL activator NA-11 is a small-molecule, selective PFKL activator, inhibits the NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type (PFKL). |
| PC-38280 |
ENPP1 inhibitor 32
ENPP1 inhibitor
|
ENPP1 inhibitor 32 is a potent, cell-impermeable small molecule inhibitor of ENPP1 with Ki of < 2 nM. |
| PC-38276 |
KL201
CRY1 modulator
|
KL201 (KL201) is an isoform-selective modulator of Cryptochrome 1 (CRY1), stabilize CRY1 but not CRY2. |
| PC-38275 |
UNC4850
CDYL1/2 inhibitor
|
UNC4850 (UNC-4850) is a specific small-molecule inhibitor toward CDY Chromodomain CDYL1/2 with Kd of 0.47/0.42 uM, >10-fold selectivity over CDY1, CBX5 and CBX7. |
| PC-38274 |
PI5P4K inhibitor 30
PI5P4K inhibitor
|
PI5P4K inhibitor 30 is a highly selective pan-PI5P4K covalent inhibitor with IC50 of 1.3/9.9 uM against PI5P4Kα/β, inhibits PI5P4Kγ by 22% at 1 uM.. |
