| Cat. No. |
Product Name |
Information |
| PC-72463 |
BAY-091
PIP4K2A inhibitor
|
BAY-091 (BAY091) is a potent and highly selective inhibitor of PIP4K2A with IC50 of 16 nM in the high ATP (2 mM) HTRF assay. |
| PC-72461 |
MLS000544460
EYA2 inhibitor
|
MLS000544460 (EYA2i) is a specific, allosteric inhibitor of Eya2 phosphatase with IC50 of 4.1 uM, KD of 2.0 uM, does not bind Eya3 ED, Eya1 and Eya4 ED. |
| PC-72451 |
NCGC00378430
SIX1-EYA2 inhibitor
|
NCGC00378430 (Compound 8430) is a novel small molecule compound that reduces the SIX1/EYA2 interaction in vitro with IC50 of 52 uM in the Alphascreen assay. |
| PC-72445 |
VLX600
Iron chelator
|
VLX600 (VLX-600) is a small molecule iron chelator and mitochondrial oxidative phosphorylation inhibitor, targets quiescent tumor cells and to inhibit mitochondrial respiration. |
| PC-72443 |
ONC212
GPR132 activator
|
ONC212 (ONC-212) is a potent anti-cancer small molecule, activator of an orphan GPCR GPR132 and Gαq signaling. |
| PC-72383 |
SRI-37330
TXNIP inhibitor
|
SRI-37330 (SRI 37330) is an orally available small molecule that regulates TXNIP expression, inhibits endogenous TXNIP mRNA expression (IC50=0.64 uM, INS-1 cells qRT-PCR assays). |
| PC-72381 |
HKB99
PGAM1 inhibitor
|
HKB99 (PGAM1 allosteric inhibitor HKB99) is a novel potent, cellularly active PGAM1 (Phosphoglycerate mutase 1) allosteric inhibitor, HKB99 is noncompetitive with the substrate 3-PG with IC50 of 0.85 uM in in vitro enzyme assays. |
| PC-72374 |
NF-56-EJ40
SUCNR1 (GPR91) antagonist
|
NF-56-EJ40 is a highly potent, human-selective antagonist of SUCNR1 (GPR91) with IC50 of 25 nM and Ki of 33 nM. |
| PC-72337 |
MAT2A inhibitor 28
MAT2A inhibitor
|
MAT2A inhibitor 28 (AZ-28) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 22 nM. |
| PC-72269 |
OP-5244
CD73 inhibitor
|
OP-5244 is a highly potent, orally bioavailable CD73 inhibitor with biochemical IC50 of 0.25 nM. |
| PC-72236 |
STF-1084
ENPP1 inhibitor
|
STF-1084 (STF1084) is a potent, cell impermeable, specific, stable, and non-toxic ENPP1 inhibitor with Ki,app of 110 nM (in vitro 32P-cGAMP TLC assay), and cellular IC50 of 340 nM. |
| PC-72215 |
BJP-06-005-3
Pin1 inhibitor
|
BJP-06-005-3 is a potent, selective, covalent, cell-permeable peptide Pin1 inhibitor (Ki=15 nM) that covalently target Cys113, a highly conserved cysteine located in the Pin1 active site. |
